Detection, numerical simulation and approximate inversion of optoacoustic signals generated in multi-layered PVA hydrogel based tissue phantoms

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Blumenrother, E.; Melchert, O.; Wollweber, M.; Roth, B.: Detection, numerical simulation and approximate inversion of optoacoustic signals generated in multi-layered PVA hydrogel based tissue phantoms. In: Photoacoustics 4 (2016), Nr. 4, S. 125-132. DOI: https://doi.org/10.1016/j.pacs.2016.10.002

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To cite the version in the repository, please use this identifier: https://doi.org/10.15488/1011

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Abstract: 
Optoacoustic (OA) measurements can not only be used for imaging purposes but as a more general tool to "sense" physical characteristics of biological tissue, such as geometric features and intrinsic optical properties. In order to pave the way for a systematic model-guided analysis of complex objects we devised numerical simulations in accordance with the experimental measurements. We validate our computational approach with experimental results observed for layered polyvinyl alcohol hydrogel samples, using melanin as the absorbing agent. Experimentally, we characterize the acoustic signal observed by a piezoelectric detector in the acoustic far-field in backward mode and we discuss the implication of acoustic diffraction on our measurements. We further attempt an inversion of an OA signal in the far-field approximation.
License of this version: CC BY 4.0 Unported
Document Type: article
Publishing status: publishedVersion
Issue Date: 2016
Appears in Collections:Forschungszentren

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pos. country downloads
total perc.
1 image of flag of Germany Germany 188 78.66%
2 image of flag of United States United States 13 5.44%
3 image of flag of China China 11 4.60%
4 image of flag of Algeria Algeria 4 1.67%
5 image of flag of No geo information available No geo information available 2 0.84%
6 image of flag of Japan Japan 2 0.84%
7 image of flag of India India 2 0.84%
8 image of flag of France France 2 0.84%
9 image of flag of Czech Republic Czech Republic 2 0.84%
10 image of flag of Hong Kong Hong Kong 1 0.42%
    other countries 12 5.02%

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