Neuser, F.; Zorn, H.; Berger, R.G.: Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus. In: Zeitschrift für Naturforschung - Section C Journal of Biosciences 55 (2000), Nr. 7-8, S. 560-568. DOI:
https://doi.org/10.1515/znc-2000-7-814
Zusammenfassung: |
The wild-type yeast strain Zygosaccharomyces bisporus CBS 702 produced a-hydroxy-ketones (acyloins) from amino acid precursors after transamination to the corresponding 2-oxo acids. The key enzyme of the subsequent decarboxylation and C-C bond forming reaction, pyruvate decarboxylase (PDC), was examined for its substrate- and stereo-specific-ity. A wide variety of saturated and unsaturated aliphatic and aromatic aldehydes was successfully converted to acyloins. 19 of the biotransformation products identified had not been reported as natural substances before. Product yields were strongly affected by substrate structure. © 2000, Verlag der Zeitschrift für Naturforschung. All rights reserved.
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Lizenzbestimmungen: |
CC BY-NC-ND 3.0 Unported - https://creativecommons.org/licenses/by-nc-nd/3.0/
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Publikationstyp: |
Article |
Publikationsstatus: |
publishedVersion |
Erstveröffentlichung: |
2000 |
Schlagwörter (englisch): |
Zygosaccharomyces bisporus, Acyloin Formation, Pyruvate Decarboxylase, chemical bond, decarboxylation, enzyme specificity, enzyme substrate, genetic strain, pyruvate decarboxylase, stereospecificity, wild relative, yeast, Zygosaccharomyces bisporus
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Fachliche Zuordnung (DDC): |
570 | Biowissenschaften, Biologie
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