Terpenes represent the largest and structurally most diverse group of natural products. Since ancient times, humans have used terpenes contained in essential oils as medicinal agents, preservatives, and fragrances in their ...

The first total synthesis of halioxepine is accomplished using a 1,4-addition for constructing the quaternary center at C10 and a halo etherification for the generation of the tertiary ether at C7. The correct structure ...