Browsing by Subject "polyketide synthases"

Browsing by Subject "polyketide synthases"

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  • An Amidinohydrolase Provides the Missing Link in the Biosynthesis of Amino Marginolactone Antibiotics 
    Hong, Hui; Samborskyy, Markiyan; Lindner, Frederick; Leadlay, Peter F. (Weinheim : Wiley Online Library, 2016)
    Desertomycin A is an aminopolyol polyketide containing a macrolactone ring. We have proposed that desertomycin A and similar compounds (marginolactones) are formed by polyketide synthases primed not with gamma-aminobutanoyl-CoA ...
  • Lessons from the Synthetic Chemist Nature 
    Juerjens, Gerrit; Kirschning, Andreas; Candito, David A. (Cambridge : Royal Society of Chemistry, 2015-03-02)
    This conceptual review examines the ideal multistep synthesis from the perspective of nature. We suggest that besides step- and redox economies, one other key to efficiency is steady state processing with intermediates ...