Auflistung nach Schlagwort "organoid"

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  • CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model 
    Brooks, Pascal; Zur Bruegge, Talke; Boyle, Erin C.; Kalies, Stefan; Villarreal, Santiago Nahuel; Liese, Andrea; Bleich, André; Buettner, Manuela (London : Hindawi Limited, 2020)
    Cd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. CD14 acts as a coreceptor for bacterial lipopolysaccharide (LPS), while ALPK1 ...
  • Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism 
    Hartleben, Goetz; Schorpp, Kenji; Kwon, Yun; Betz, Barbara; Tsokanos, Foivos-Filippos; Dantes, Zahra; Schäfer, Arlett; Rothenaigner, Ina; Monroy Kuhn, José Manuel; Morigny, Pauline; Mehr, Lisa; Lin, Sean; Seitz, Susanne; Tokarz, Janina; Artati, Anna; Adamsky, Jerzy; Plettenburg, Oliver; Lutter, Dominik; Irmler, Martin; Beckers, Johannes; Reichert, Maximilian; Hadian, Kamyar; Zeigerer, Anja; Herzig, Stephan; Berriel Diaz, Mauricio (Weinheim : Wiley-VCH, 2021)
    By accentuating drug efficacy and impeding resistance mechanisms, combinatorial, multi-agent therapies have emerged as key approaches in the treatment of complex diseases, most notably cancer. Using high-throughput drug ...
  • Investigation of Colonic Regeneration via Precise Damage Application Using Femtosecond Laser-Based Nanosurgery 
    Donath, Sören; Angerstein, Leon; Gentemann, Lara; Müller, Dominik; Seidler, Anna E.; Jesinghaus, Christian; Bleich, André; Heisterkamp, Alexander; Buettner, Manuela; Kalies, Stefan (Basel : MDPI, 2022)
    Organoids represent the cellular composition of natural tissue. So called colonoids, organoids derived from colon tissue, are a good model for understanding regeneration. However, next to the cellular composition, the ...