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A novel shape memory plate osteosynthesis for noninvasive modulation of fixation stiffness in a rabbit tibia osteotomy model

Müller, Christian W.; Pfeifer, Ronny; Meier, Karen; Decker, Sebastian; Reifenrath, Janin; Gösling, Thomas; Wesling, Volker; Krettek, Christian; Hurschler, Christof; Krämer, Manuel (New York, NY : Hindawi Publishing Corporation, 2015)

Nickel-titanium shape memory alloy (NiTi-SMA) implants might allow modulating fracture healing, changing their stiffness through alteration of both elastic modulus and cross-sectional shape by employing the shape memory ...
Abdominal obesity‐related disturbance of insulin sensitivity is associated with cd8+ emra cells in the elderly

Boßlau, Tim K.; Wasserfurth, Paulina; Krüger, Britta; Reichel, Thoma; Palmowski, Jana; Nebl, Josefine; Weyh, Christopher; Schenk, Alexander; Joisten, Niklas; Stahl, Frank; Thoms, Stefanie; Gebhardt, Kristina; Hahn, Andreas; Krüger, Karsten (Basel : MDPI, 2021)

Aging and overweight increase the risk of developing type 2 diabetes mellitus. In this cross‐sectional study, we aimed to investigate the potential mediating role of T‐EMRA cells and inflammatory markers in the development ...
The acquisition of plural marking in English and German revisited: Schemata versus rules

Köpcke, Klaus-Michael (Cambridge : Cambridge University Press, 1998)

[No abstract available]
Adhesion, Vitality and Osteogenic Differentiation Capacity of Adipose Derived Stem Cells Seeded on Nitinol Nanoparticle Coatings

Strauß, Sarah; Neumeister, Anne; Barcikowski, Stephan; Kracht, Dietmar; Kuhbier, Jörn W.; Radtke, Christine; Reimers, Kerstin; Vogt, Peter M. (San Francisco, California, US : PLOS, 2013)

Autologous cells can be used for a bioactivation of osteoimplants to enhance osseointegration. In this regard, adipose derived stem cells (ASCs) offer interesting perspectives in implantology because they are fast and easy ...
Auditory proprioceptive integration: Effects of real-time kinematic auditory feedback on knee proprioception

Ghai, Shashank; Schmitz, Gerd; Hwang, Tong-Hun; Effenberg, Alfred O. (Lausanne : Frontiers Media S.A., 2018)

The purpose of the study was to assess the influence of real-time auditory feedback on knee proprioception. Thirty healthy participants were randomly allocated to control (n = 15), and experimental group I (15). The ...
Biologic TNF inhibiting agents for treatment of inflammatory rheumatic diseases: Dosing patterns and related costs in Switzerland from a payers perspective

Zeidler, Jan; Mittendorf, Thomas; Müller, Rüdiger; Kempis, Johannes von (Heidelberg : Springer Verlag, 2012)

Background: To obtain detailed real-life data on costs and dosing patterns in the utilisation of the TNF inhibitors adalimumab, etanercept, and infliximab in patients treated in Switzerland. Methods: Administrative claims ...
Cancer cell-selective, clathrin-mediated endocytosis of aptamer decorated nanoparticles

Engelberg, Shira; Modrejewski, Julia; Walter, Johanna-Gabriela; Livney, Yoav D.; Assaraf, Yehuda G. (S.l. : Impact Journals LLC, 2018)

Lung cancer is the leading cause of cancer mortality worldwide, resulting in 88% deaths of all diagnosed patients. Hence, novel therapeutic modalities are urgently needed. Single-stranded oligonucleotide-based aptamers ...
CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model

Brooks, Pascal; Zur Bruegge, Talke; Boyle, Erin C.; Kalies, Stefan; Villarreal, Santiago Nahuel; Liese, Andrea; Bleich, André; Buettner, Manuela (London : Hindawi Limited, 2020)

Cd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. CD14 acts as a coreceptor for bacterial lipopolysaccharide (LPS), while ALPK1 ...
Clastogenic Effect of Carthamus lanatus L. (Asteraceae)

Topashka-Ancheva, Margarita; Taskova, Rilka M.; Handjieva, Nedjalka; Mikhova, Bozhanka; Duddeck, Helmut (Berlin : De Gruyter, 2003)

The clastogenic effect of total dichloromethane, methanol and water extracts, four bioactive fractions and three individual constituents from Carthamus lanatus aerial parts were evaluated in mice by bone marrow chromosome ...
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

Hartleben, Goetz; Schorpp, Kenji; Kwon, Yun; Betz, Barbara; Tsokanos, Foivos-Filippos; Dantes, Zahra; Schäfer, Arlett; Rothenaigner, Ina; Monroy Kuhn, José Manuel; Morigny, Pauline; Mehr, Lisa; Lin, Sean; Seitz, Susanne; Tokarz, Janina; Artati, Anna; Adamsky, Jerzy; Plettenburg, Oliver; Lutter, Dominik; Irmler, Martin; Beckers, Johannes; Reichert, Maximilian; Hadian, Kamyar; Zeigerer, Anja; Herzig, Stephan; Berriel Diaz, Mauricio (Weinheim : Wiley-VCH, 2021)

By accentuating drug efficacy and impeding resistance mechanisms, combinatorial, multi-agent therapies have emerged as key approaches in the treatment of complex diseases, most notably cancer. Using high-throughput drug ...
Comparison of plasma responses human subjects after the ingestion of 3R,3R′-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R′-zeaxanthin using chiral high-performance liquid chromatography

Breithaupt, Dietmar E.; Weller, Philipp; Wolters, Maike; Hahn, Andreas (Cambridge : Cambridge University Press, 2004)

Age-related macular degeneration (AMD) is one of the most common eye diseases of elderly individuals. It has been suggested that lutein and zeaxanthin may reduce the risk for AMD. Information concerning the absorption of ...
Consumer preferences for food labels on tomatoes in Germany - A comparison of a quasi-experiment and two stated preference approaches

Meyerding, Stephan G.H. (Amsterdam : Elsevier, 2016)

In many studies, consumer preferences are determined by using direct surveys. For this method social desirability is problematic. This leads to the effect that participants answer in a way that they perceive as desired by ...
Costs and treatment patterns of incident ADHD patients - a comparative analysis before and after the initial diagnosis -

Klora, Mike; Zeidler, Jan; Linder, Roland; Verheyen, Frank; Schulenburg, Johann-Matthias Graf von der (Heidelberg : Springer Verlag, 2015)

Background and objectives: The costs and treatment patterns of attention deficit hyperactivity disorder (ADHD) are subjects of health services research in Germany and worldwide. Previous publications focused mainly on ...
The costs of schizophrenia and predictors of hospitalisation from the statutory health insurance perspective

Zeidler, Jan; Slawik, Lara; Fleischmann, Jochen; Greiner, Wolfgang (Heidelberg : Springer Verlag, 2012)

Background: The aim of the study was to determine the costs of treating schizophrenia from the perspective of the statutory health insurance, as well as the identification of predictors of hospitalisation of formerly stable ...
Diet-dependent net endogenous acid load of vegan diets in relation to food groups and bone health-related nutrients: Results from the German Vegan Study

Ströhle, Alexander; Waldmann, Annika; Koschizke, Jochen; Leitzmann, Claus; Hahn, Andreas (Basel : S. Karger AG, 2011)

Background/Aims:Dietary composition has been shown to affect acid-base homeostasis and bone health in humans. We investigated the potential renal acid load (PRAL) and the estimated diet-dependent net acid load (net endogenous ...
Dietary intake of vitamin B6 and concentration of vitamin B 6 in blood samples of German vegans

Waldmann, A.; Dörr, B.; Koschizke, J.W.; Leitzmann, C.; Hahn, A. (Cambridge : Cambridge University Press, 2006)

Objective: The study aimed to evaluate the dietary vitamin B6 intake and determine the vitamin B6 concentration in blood samples of German vegans. Design and setting: Cross-sectional study with 33 examination sites all ...
Do preschools differ in promoting children's physical activity? An instrument for the assessment of preschool physical activity programmes

Sterdt, Elena; Pape, Natalie; Kramer, Silke; Urban, Michael; Werning, Rolf; Walter, Ulla (London : BioMed Central Ltd., 2013)

Background: Preschools offer high potential for preventive interventions. However, little is known about the structure of preschool programmes to promote physical activity (PA) in preschoolers although almost all children ...
Effect of rhythmic auditory cueing on aging gait: A systematic review and meta-analysis

Ghai, Shashank; Ghai, Ishan; Effenberg, Alfred O. (Fort Worth : International Society on Aging and Disease, 2018)

Rhythmic auditory cueing has been widely used in gait rehabilitation over the past decade. The entrainment effect has been suggested to introduce neurophysiological changes, alleviate auditory-motor coupling and reduce ...
Evaluation of incidence rates in pre-clinical studies using a williams-type procedure

Hothorn, Ludwig A.; Sill, Martin; Schaarschmidt, Frank (Berlin : De Gruyter, 2010)

The analysis of dose-response relationships is a common problem in pre-clinical studies. For example, proportions such as mortality rates and histopathological findings are of particular interest in repeated toxicity ...
First-in-class positron emission tomography tracer for the glucagon receptor

Velikyan, Irina; Haack, Torsten; Bossart, Martin; Evers, Andreas; Laitinen, Ilina; Larsen, Philip; Plettenburg, Oliver; Johansson, Lars; Pierrou, Stefan; Wagner, Michael; Eriksson, Olof (Heidelberg : Springer Verlag, 2019)

Abstract: The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially as part of the pharmacology of dual glucagon-like peptide-1/glucagon (GLP-1/GCG) receptor agonists. However, ...

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