Novel surface coatings of percutaneous implants need to be tested in biocompatibility studies. The use of animal models for testing usually involves numerous lethal biopsies for the analysis of the implant-tissue interface. ...

In vivo Raman spectroscopy with low signal-to-noise ratio and strong, irregularly shaped fluorescence background imposes a challenge for automatic baseline correction methods. In this work, an approach that enables fast ...

Toxicity testing nowadays plays a critical role in decision-making, and in vivo animal studies are still required for hazard assessment. Toxicity assessment of the 21st century, however, aims to replace in vivo studies ...

This thesis presents a fast, reliable, and non-invasive method for in vivo thickness determination of melanocytic nevi, and melanomas in particular. Such a tool is highly desirable for clinical dermatology as it may ...