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Ablation of Red Stable Transfected Claudin Expressing Canine Prostate Adenocarcinoma and Transitional Cell Carcinoma Cell Lines by C-CPE Gold-Nanoparticle-Mediated Laser Intervention

Alnajjar, Suhayla; Nolte, Ingo; Becker, Annegret; Schille, Jan Torben; Trakooljul, Nares; Frank, Marcus; Ngezahayo, Anaclet; Murua Escobar, Hugo (Basel : Molecular Diversity Preservation International (MDPI), 2021)

Claudin (CLDN) proteins are commonly expressed in cancers and targeted in novel therapeutic approaches. The C-terminal of Clostridium perfringens enterotoxin (C-CPE) efficiently binds several claudins. In this study, ...
Co-transfection of plasmid DNA and laser-generated gold nanoparticles does not disturb the bioactivity of GFP-HMGB1 fusion protein

Petersen, Svea; Soller, Jan T.; Wagner, Siegfried; Richter, Andreas; Bullerdiek, Jörn; Nolte, Ingo; Barcikowski, Stephan; Murua Escobar, Hugo (London : Biomed Central, 2009)

Ultrashort pulsed laser ablation in liquids represents a powerful tool for the generation of pure gold nanoparticles (AuNPs) avoiding chemical precursors and thereby making them especially interesting for biomedical ...
Gold Nanoparticle Mediated Laser Transfection for Efficient siRNA Mediated Gene Knock Down

Heinemann, Dag; Schomaker, Markus; Kalies, Stefan; Schieck, Maximilian; Carlson, Regina; Murua Escobar, Hugo; Ripken, Tammo; Meyer, Heiko; Heisterkamp, Alexander (San Francisco, California, US : PLOS, 2013)

Laser based transfection methods have proven to be an efficient and gentle alternative to established molecule delivery methods like lipofection or electroporation. Among the laser based methods, gold nanoparticle mediated ...
Investigation of biophysical mechanisms in gold nanoparticle mediated laser manipulation of cells using a multimodal holographic and fluorescence imaging setup

Kalies, Stefan; Antonopoulos, Georgios C.; Rakoski, Mirko S.; Heinemann, Dag; Schomaker, Markus; Ripken, Tammo; Meyer, Heiko (San Francisco, CA : Public Library of Science (PLoS), 2015)

Laser based cell manipulation has proven to be a versatile tool in biomedical applications. In this context, combining weakly focused laser pulses and nanostructures, e.g. gold nanoparticles, promises to be useful for high ...
Lateral Flow Test zur Abstoßungsdiagnostik mittels Antikörper

Seiler, Lisa Katharina (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2021)

Nierentransplantationen gehören zu den häufigsten Transplantationen weltweit. Nierentrans-plantatempfänger unterziehen sich regelmäßigen Untersuchungen, u. a. um eine Nierenabsto-ßung frühzeitig festzustellen. Für die ...
Low-frequency magnetic response of gold nanoparticles

Harke, Saba; Habibpourmoghadam, Atefeh; Evlyukhin, Andrey B.; Calà Lesina, Antonio; Chichkov, Boris N. ([London] : Macmillan Publishers Limited, part of Springer Nature, 2023)

Gold nanoparticles (AuNPs) exposed to low frequency magnetic fields have shown promise in enhancing biological processes, such as cellular reprogramming. Despite the experimental evidence, a comprehensive understanding of ...
Optical and electron microscopy study of laser-based intracellular molecule delivery using peptide-conjugated photodispersible gold nanoparticle agglomerates

Krawinkel, Judith; Richter, Undine; Torres-Mapa, Maria Leilani; Westermann, Martin; Gamrad, Lisa; Rehbock, Christoph; Barcikowski, Stephan; Heisterkamp, Alexander (London : BioMed Central Ltd., 2016)

Background: Cell-penetrating peptides (CPPs) can act as carriers for therapeutic molecules such as drugs and genetic constructs for medical applications. The triggered release of the molecule into the cytoplasm can be ...

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