Background: Advanced therapy medicinal products (ATMPs) are beginning to reach European markets, and questions are being asked about their value for patients and how healthcare systems should pay for them. Objectives: To ...

Objective: Evaluation of the costs of a population-based genetic hemochromatosis (HH) screening. Methods: We performed a decision tree analysis and subsequently quantified the screening and treatment costs and the effect ...

For the economic use of repair in the spare parts business, additive repair by Laser Powder Bed Fusion (LPBF) is a promising technology. As material can only be applied to a flat surface in LPBF, prior machining is required. ...

In the past years, stakeholder engagement has become more important in flood risk management. On the one hand stakeholder engagement is often declared as a better way of management, a more successful way to reach consensus ...

[No abstract available]

Dr Philipp Koeker describes the benefits and challenges of using mixed-methods research. His study investigated how and why Eastern European presidents use their veto powers, mixing statistical analysis and elite interviews.

Background: Despite diverging definitions on rare conditions, people suffering from rare diseases share similar difficulties. A lack of experience by health professionals, a long wait from first symptoms to diagnosis, ...

Deformation monitoring usually focuses on the detection of whether the monitored objects satisfy the given properties (e.g. being stable or not), and makes further decisions to minimise the risks, for example, the consequences ...