Browsing by Subject "clinical research"

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  • Müller, Katharina F.; Briel, Matthias; Strech, Daniel; Meerpohl, Jörg J.; Lang, Britta; Motschall, Edith; Gloy, Viktoria; Lamontagne, Francois; Bassler, Dirk (San Francisco : Public Library of Science, 2014)
    Background: Systematic reviews of preclinical studies, in vivo animal experiments in particular, can influence clinical research and thus even clinical care. Dissemination bias, selective dissemination of positive or ...
  • Strech, Daniel; Metz, Courtney; Knüppel, Hannes (San Francisco : Public Library of Science, 2014)
    Introduction: According to the Declaration of Helsinki and other guidelines, clinical studies should be approved by a research ethics committee and seek valid informed consent from the participants. Editors of medical ...
  • Kaye, Jane; Hurles, Matthew; Griffin, Heather; Grewal, Jasjote; Bobrow, Martin; Timpson, Nic; Smee, Carol; Bolton, Patrick; Durbin, Richard; Dyke, Stephanie; Fitzpatrick, David; Kennedy, Karen; Kent, Alastair; Muddyman, Dawn; Muntoni, Francesco; Raymond, Lucy F.; Semple, Robert; Spector, Tim (London : Nature Publishing Group, 2014)
    Recent advances in sequencing technology allow data on the human genome to be generated more quickly and in greater detail than ever before. Such detail includes findings that may be of significance to the health of the ...
  • Nuijten, M.J.C.; Mittendorf, Thomas; Persson, Uwe (Heidelberg : Springer Verlag, 2011)
    The objective of this paper was to address the importance of dealing systematically and comprehensively with uncertainty in a budget impact analysis (BIA) in more detail. The handling of uncertainty in health economics was ...