Auflistung nach Schlagwort "aptamer"

Sortiert nach: Sortierung: Ergebnisse:

  • 3D-printed microfluidics integrated with optical nanostructured porous aptasensors for protein detection 
    Arshavsky-Graham, Sofia; Enders, Anton; Ackerman, Shanny; Bahnemann, Janina; Segal, Ester (Wien [u.a.] : Springer, 2021)
    Microfluidic integration of biosensors enables improved biosensing performance and sophisticated lab-on-a-chip platform design for numerous applications. While soft lithography and polydimethylsiloxane (PDMS)-based ...
  • An Antibody-Aptamer-Hybrid Lateral Flow Assay for Detection of CXCL9 in Antibody-Mediated Rejection after Kidney Transplantation 
    Seiler, Lisa K.; Phung, Ngoc Linh; Nikolin, Christoph; Immenschuh, Stephan; Erck, Christian; Kaufeld, Jessica; Haller, Hermann; Falk, Christine S.; Jonczyk, Rebecca; Lindner, Patrick; Thoms, Stefanie; Siegl, Julia; Mayer, Günter; Feederle, Regina; Blume, Cornelia A. (Basel : MDPI, 2022)
    Chronic antibody-mediated rejection (AMR) is a key limiting factor for the clinical outcome of a kidney transplantation (Ktx), where early diagnosis and therapeutic intervention is needed. This study describes the ...
  • Aptamer Microarrays-Current Status and Future Prospects 
    Witt, Martin; Walter, Johanna-Gabriela; Stahl, Frank (Basel : MDPI AG, 2015)
    Microarray technologies are state of the art in biological research, which requires fast genome, proteome and transcriptome analysis technologies. Often antibodies are applied in protein microarrays as proteomic tools. ...
  • Aptamer-based optical biosensors 
    Urmann, Katharina (Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2016)
    [no abstract]
  • Aptamer-modified nanomaterials: Principles and applications 
    Urmann, Katharina; Modrejewski, Julia; Scheper, Thomas; Walter, Johanna-Gabriela (Berlin : Walter de Gruyter, 2017)
    Aptamers are promising alternative binders that can substitute antibodies in various applications. Due to the advantages of aptamers, namely their high affinity, specificity and stability, along with the benefits originating ...
  • Aptamer-modified polymer nanoparticles for targeted drug delivery 
    Modrejewski, Julia; Walter, Johanna-Gabriela; Kretschmer, Imme; Kemal, Evren; Green, Mark; Belhadj, Hamza; Blume, Cornelia; Scheper, Thomas (Berlin : De Gruyter, 2016)
    The purpose of this study was to develop a model system for targeted drug delivery. This system should enable targeted drug release at a certain tissue in the body. In conventional drug delivery systems, drugs are often ...
  • Aptasensoren für kleine Moleküle anhand des Beispiels 25-Hydroxy-Vitamin D3 
    Prante, Marc (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2021)
    Substances with a low molecular weight (< 900 Da) are classified as small molecules and are ubiquitous in nature and in the human body. Small molecules can be found in the environment where they are produced as secondary ...
  • Aptasensors for Point-of-Care Detection of Small Molecules 
    Prante, Marc; Segal, Ester; Scheper, Thomas; Bahnemann, Janina; Walter, Johanna (Basel : Molecular Diversity Preservation International (MDPI), 2020)
    Aptamers, a group of nucleic acids which can specifically bind to a target molecule, have drawn extensive interest over the past few decades. For analytics, aptamers represent a viable alternative to gold-standard antibodies ...
  • Aptasensors versus immunosensors—Which will prevail? 
    Arshavsky-Graham, Sofia; Heuer, Christopher; Jiang, Xin; Segal, Ester (Engineering in life sciences, 2022)
    Since the invention of the first biosensors 70 years ago, they have turned into valuable and versatile tools for various applications, ranging from disease diagnosis to environmental monitoring. Traditionally, antibodies ...
  • Cancer cell-selective, clathrin-mediated endocytosis of aptamer decorated nanoparticles 
    Engelberg, Shira; Modrejewski, Julia; Walter, Johanna-Gabriela; Livney, Yoav D.; Assaraf, Yehuda G. (S.l. : Impact Journals LLC, 2018)
    Lung cancer is the leading cause of cancer mortality worldwide, resulting in 88% deaths of all diagnosed patients. Hence, novel therapeutic modalities are urgently needed. Single-stranded oligonucleotide-based aptamers ...
  • Characterization of an Aptamer Directed against 25-Hydroxyvitamin D for the Development of a Competitive Aptamer-Based Assay 
    Prante, Marc; Schüling, Torsten; Roth, Bernhard; Bremer, Kort; Walter, Johanna (Basel : MDPI AG, 2019)
    Detection of the small molecule 25-hydroxyvitamin D (25(OH)D) as the most relevant marker for vitamin D supply suffers from a high variability of results using the current detection methods, such as high-performance liquid ...
  • Einsatz Aptamer-modifizierter Gold-Nanopartikel in der Diagnostik 
    Eilers, Alina (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2021)
    Ein Lateral Flow Assay (LFA) ermöglicht eine schnelle Detektion von Krankheitserregern, Hormonen oder Verunreinigungen. Gleichzeitig sind LFAs kostengünstig und einfach anwendbar, so dass sie auch von nicht fachkundigen ...
  • On Chip Protein Pre-Concentration for Enhancing the Sensitivity of Porous Silicon Biosensors 
    Arshavsky-Graham, Sofia; Massad-Ivanir, Naama; Paratore, Federico; Scheper, Thomas; Bercovici, Moran; Segal, Ester (Washington D.C. : American Chemical Society, 2017)
    Porous silicon (PSi) nanomaterials have been widely studied as label-free optical biosensors for protein detection. However, these biosensors’ performance, specifically in terms of their sensitivity (which is typically in ...
  • Porous silicon biosensors for protein targets: modelling and sensitivity enhancement 
    Arshavsky-Graham, Sofia (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2021-08)
    Nanostructured porous silicon (PSi) films have been widely studied for the past two decades as optical transducers for the detection of various molecules, with advantages of simple fabrication, high internal surface, ...
  • SPR Biosensor Based on Polymer Multi-Mode Optical Waveguide and Nanoparticle Signal Enhancement 
    Walter, Johanna-Gabriela; Eilers, Alina; Alwis, Lourdes Shanika Malindi; Roth, Bernhard Wilhelm; Bremer, Kort (Basel : MDPI, 2020)
    We present a surface plasmon resonance (SPR) biosensor that is based on a planar-optical multi-mode (MM) polymer waveguide structure applied for the detection of biomolecules in the lower nano-molar (nM) range. The basic ...