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Design, Synthese und molekularbiologische Evaluierung synthetischer Ribonucleasen mit Cyclen-Grundgerüst

Michaelis, Katrin (Hannover : Universität, 2001)

[no abstract]
Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: Results from a randomized controlled trial

Schmidt, Simone; Stahl, Frank; Mutz, Kai-Oliver; Scheper, Thomas; Hahn, Andreas; Schuchardt, Jan Philipp (London : BioMed Central Ltd., 2012)

Background: Epidemiological studies have suggested the benefits of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cardiovascular health, but only limited data are available describing n-3 PUFA regulated pathways in ...
Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples

Bajerski, F.; Bürger, A.; Glasmacher, B.; Keller, E.R.J.; Müller, K.; Mühldorfer, K.; Nagel, M.; Rüdel, H.; Müller, T.; Schenkel, J.; Overmann, J. (Heidelberg : Springer Verlag, 2020)

The availability of bioresources is a precondition for life science research, medical applications, and diagnostics, but requires a dedicated quality management to guarantee reliable and safe storage. Anecdotal reports of ...
Identification of RNA Base Pairs and Complete Assignment of Nucleobase Resonances by Proton-Detected Solid-State NMR Spectroscopy at 100 kHz MAS

Aguion, Philipp Innig; Kirkpatrick, John; Carlomagno, Teresa; Marchanka, Alexander (Weinheim : Wiley-VCH, 2021)

Knowledge of RNA structure, either in isolation or in complex, is fundamental to understand the mechanism of cellular processes. Solid-state NMR (ssNMR) is applicable to high molecular-weight complexes and does not require ...
Interaction of the spliced Oskar localization element of Oskar mRNA with the protein PYM

Hegde, Veena (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2023-03)

mRNAs and the process of mRNA localization are the fundamental and pivotal parts of cellular functions. mRNA localization encompasses an important role in cellular differentiation and site-specific cellular functions, from ...
Laser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers

Walter, Johanna-Gabriela; Petersen, Svea; Stahl, Frank; Scheper, Thomas; Barcikowski, Stephan (London : Biomed Central Ltd., 2010)

Background: Bio-conjugated nanoparticles are important analytical tools with emerging biological and medical applications. In this context, in situ conjugation of nanoparticles with biomolecules via laser ablation in an ...
Specific Signal Enhancement on an RNA-Protein Interface by Dynamic Nuclear Polarization

Aladin, Victoria; Sreemantula, Arun K.; Biedenbänder, Thomas; Marchanka, Alexander; Corzilius, Björn (Weinheim : VCH Verl.-Ges., 2022)

Sensitivity and specificity are both crucial for the efficient solid-state NMR structure determination of large biomolecules. We present an approach that features both advantages by site-specific enhancement of NMR ...
Strategies for RNA Resonance Assignment by 13C/15N- and 1H-Detected Solid-State NMR Spectroscopy

Aguion, Philipp Innig; Marchanka, Alexander (Lausanne : Frontiers, 2021)

Magic angle spinning (MAS) solid-state NMR (ssNMR) is an established tool that can be applied to non-soluble or non-crystalline biomolecules of any size or complexity. The ssNMR method advances rapidly due to technical ...
Structural basis for the substrate specificity and catalytic features of pseudouridine kinase from Arabidopsis thaliana

Kim, Sang-Hoon; Witte, Claus-Peter; Rhee, Sangkee (Basel : MDPI AG, 2021)

RNA modifications can regulate the stability of RNAs, mRNA-protein interactions, and translation efficiency. Pseudouridine is a prevalent RNA modification, and its metabolic fate after RNA turnover was recently characterized ...
Structural studies of 5´ UTR of Hepatitis C viral RNA by NMR-based structural biology

Vitsyna, Olga Alexandrovna (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2023)

RNA is a single-stranded biopolymer that plays a myriad of roles in physiological and pathological processes and is the carrier of genetic information in many human pathogens. Hepatitis C virus (HCV) is one of the most ...
Structure of the multi-subunit chloroplast RNA polymerase

do Prado, Paula F.V.; Ahrens, Frederik M.; Liebers, Monique; Ditz, Noah; Braun, Hans-Peter; Pfannschmidt, Thomas; Hillen, Hauke S. (New York, NY : Elsevier, 2024)

Chloroplasts contain a dedicated genome that encodes subunits of the photosynthesis machinery. Transcription of photosynthesis genes is predominantly carried out by a plastid-encoded RNA polymerase (PEP), a nearly 1 MDa ...

Now showing items 1-11 of 11

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