Auflistung nach Schlagwort "Genotoxicity"

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  • In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data 
    Tug, Timur; Duda, Julia C.; Menssen, Max; Bruce, Shannon Wilson; Bringezu, Frank; Dammann, Martina; Frötschl, Roland; Harm, Volker; Ickstadt, Katja; Igl, Bernd-Wolfgang; Jarzombek, Marco; Kellner, Rupert; Lott, Jasmin; Pfuhler, Stefan; Plappert-Helbig, Ulla; Rahnenführer, Jörg; Schulz, Markus; Vaas, Lea; Vasquez, Marie; Ziegler, Verena; Ziemann, Christina (Amsterdam [u.a.] : Elsevier, 2024)
    The alkaline comet assay is frequently used as in vivo follow-up test within different regulatory environments to characterize the DNA-damaging potential of different test items. The corresponding OECD Test guideline 489 ...
  • Synthesis and in vitro characterization of the genotoxic, mutagenic and cell-transforming potential of nitrosylated heme 
    Kostka, Tina; Fohrer, Jörg; Guigas, Claudia; Briviba, Karlis; Seiwert, Nina; Fahrer, Jörg; Steinberg, Pablo; Empl, Michael T. (Berlin : Springer, 2020)
    Data from epidemiological studies suggest that consumption of red and processed meat is a factor contributing to colorectal carcinogenesis. Red meat contains high amounts of heme, which in turn can be converted to its ...