Browsing by Subject "Dye transfer"

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Concatenation of human connexin26 (hCx26) and human connexin46 (hCx46) for the analysis of heteromeric gap junction hemichannels and heterotypic gap junction channels

Schadzek, Patrick; Hermes, Doris; Stahl, Yannick; Dilger, Nadine; Ngezahayo, Anaclet (Basel : MDPI AG, 2018)

Gap junction channels and hemichannels formed by concatenated connexins were analyzed. Monomeric (hCx26, hCx46), homodimeric (hCx46-hCx46, hCx26-hCx26), and heterodimeric (hCx26-hCx46, hCx46-hCx26) constructs, coupled to ...
Data of the molecular dynamics simulations of mutations in the human connexin46 docking interface

Schadzek, Patrik; Schlingmann, Barbara; Schaarschmidt, Frank; Lindner, Julia; Koval, Michael; Heisterkamp, Alexander; Ngezahayo, Anaclet; Preller, Matthias (Amsterdam : Elsevier, 2016)

The structure of hCx26 derived from the X-ray analysis was used to generate a homology model for hCx46. Interacting connexin molecules were used as starting model for the molecular dynamics (MD) simulation using NAMD and ...

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