Browsing by Subject "Biosynthesis"

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  • Hemmerling, Franziska; Hahn, Frank (Frankfurt am Main : Beilstein-Institut zur Förderung der Chemischen Wissenschaften, 2016)
    This review highlights the biosynthesis of heterocycles in polyketide natural products with a focus on oxygen and nitrogen-containing heterocycles with ring sizes between 3 and 6 atoms. Heterocycles are abundant structural ...
  • Szwalbe, Agniezka J.; Williams, Katherine; Song, Zhongshu; De Mattos-Shipley, Kate M.J.; Vincent, Jason L.; Bailey, Andrew M.; Willis, Christine L.; Cox, Russell J.; Simpson, Thomas J. (Cambridge : Royal Society of Chemistry, 2019)
    Two new dihydroxy-xanthone metabolites, agnestins A and B, were isolated from Paecilomyces variotii along with a number of related benzophenones and xanthones including monodictyphenone. The structures were elucidated by ...
  • Williams, Katherine; Szwalbe, Agnieszka J.; Mulholland, Nicholas P.; Vincent, Jason L.; Bailey, Andrew M.; Willis, Christine L.; Simpson, Thomas J.; Cox, Russell J. (Weinheim : Wiley-VCH Verlag, 2016)
    Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9-membered carbocycles with one or two fused maleic anhydride moieties. The biosynthesis of byssochlamic acid (a ...
  • Chen, Wanping; Chen, Runfa; Liu, Qingpei; He, Yi; He, Kun; Ding, Xiaoli; Kang, Lijing; Guo, Xiaoxiao; Xie, Nana; Zhou, Youxiang; Lu, Yuanyuan; Cox, Russell J.; Molnár, Istvan; Li, Mu; Shao, Yanchun; Chen, Fusheng (Cambridge : Royal Society of Chemistry, 2017)
    Monascus azaphilone pigments (MonAzPs) are very widely used as food colorants, but their biosynthetic pathway has remained poorly characterized for more than half a century. In this study, the individual steps of MonAzPs ...
  • Lebe, Karen E.; Cox, Russell J. (Cambridge : Royal Society of Chemistry, 2018)
    The squalestatins are a class of highly complex fungal metabolites which are potent inhibitors of squalene synthase with potential use in the control of cholesterol biosynthesis. Little is known of the chemical steps ...
  • De Mattos-Shipley, Kate M.J.; Greco, Claudio; Heard, David M.; Hough, Gemma; Mulholland, Nicholas P.; Vincent, Jason L.; Micklefield, Jason; Simpson, Thomas J.; Willis, Christine L.; Cox, Russell J.; Bailey, Andrew M. (Cambridge : Royal Society of Chemistry, 2018)
    The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the reported insecticidal activity of the minor metabolite, ...