Browsing by Subject "Biochemistry"

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  • Frister, Thore; Hartwig, Steffen; Alemdar, Semra; Schnatz, Katharina; Thöns, Laura; Scheper, Thomas; Beutel, Sascha (New York City, NY : Springer Humana Press Inc., 2015)
    The patchoulol synthase (PTS) is a multi-product sesquiterpene synthases which is the central enzyme for biosynthesis of patchouli essential oil in the patchouli plant. Sesquiterpene synthases catalyse the formation of ...
  • Szwalbe, Agniezka J.; Williams, Katherine; Song, Zhongshu; De Mattos-Shipley, Kate M.J.; Vincent, Jason L.; Bailey, Andrew M.; Willis, Christine L.; Cox, Russell J.; Simpson, Thomas J. (Cambridge : Royal Society of Chemistry, 2019)
    Two new dihydroxy-xanthone metabolites, agnestins A and B, were isolated from Paecilomyces variotii along with a number of related benzophenones and xanthones including monodictyphenone. The structures were elucidated by ...
  • Lönne, Maren; Bolten, Svenja Nicolin; Lavrentieva, Antonina; Stahl, Frank; Scheper, Thomas; Walter, Johanna-Gabriela (Amsterdam : Elsevier B.V., 2015)
    Since aptamers bind their targets with high affinity and specificity, they are promising alternative ligands in protein affinity purification. As aptamers are chemically synthesized oligonucleotides, they can be easily ...
  • Bolten, Svenja Nicolin; Rinas, Ursula; Scheper, Thomas (Heidelberg : Springer Verlag, 2018)
    Heparin is a highly sulfated polysaccharide which belongs to the family of glycosaminoglycans. It is involved in various important biological activities. The major biological purpose is the inhibition of the coagulation ...
  • Williams, Katherine; Szwalbe, Agnieszka J.; Mulholland, Nicholas Phillip; Vincent, Jason Leigh; Bailey, Andy M.; Willis, Christine L.; Simpson, Thomas J.; Cox, Russell J. (Weinheim : Wiley-VCH, 2016)
    Die von Pilzen produzierten Maleidride sind eine wichtige Klasse bioaktiver Sekundarmetaboliten, die aus sieben-, acht- oder neungliedrigen Carbocyclen bestehen. Jeder Cyclus ist mit einem oder zwei anellierten ...
  • Williams, Katherine; Szwalbe, Agnieszka J.; Mulholland, Nicholas P.; Vincent, Jason L.; Bailey, Andrew M.; Willis, Christine L.; Simpson, Thomas J.; Cox, Russell J. (Weinheim : Wiley-VCH Verlag, 2016)
    Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9-membered carbocycles with one or two fused maleic anhydride moieties. The biosynthesis of byssochlamic acid (a ...
  • Thurotte, Adrien; Brüser, Thomas; Mascher, Thorsten; Schneider, Dirk (London : Informa UK Limited, 2017)
    PspA, IM30 (Vipp1) and LiaH, which all belong to the PspA/IM30 protein family, form high molecular weight oligomeric structures. For all proteins membrane binding and protection of the membrane structure and integrity has ...
  • Chen, Wanping; Chen, Runfa; Liu, Qingpei; He, Yi; He, Kun; Ding, Xiaoli; Kang, Lijing; Guo, Xiaoxiao; Xie, Nana; Zhou, Youxiang; Lu, Yuanyuan; Cox, Russell J.; Molnár, Istvan; Li, Mu; Shao, Yanchun; Chen, Fusheng (Cambridge : Royal Society of Chemistry, 2017)
    Monascus azaphilone pigments (MonAzPs) are very widely used as food colorants, but their biosynthetic pathway has remained poorly characterized for more than half a century. In this study, the individual steps of MonAzPs ...
  • Lebe, Karen E.; Cox, Russell J. (Cambridge : Royal Society of Chemistry, 2018)
    The squalestatins are a class of highly complex fungal metabolites which are potent inhibitors of squalene synthase with potential use in the control of cholesterol biosynthesis. Little is known of the chemical steps ...
  • De Mattos-Shipley, Kate M.J.; Greco, Claudio; Heard, David M.; Hough, Gemma; Mulholland, Nicholas P.; Vincent, Jason L.; Micklefield, Jason; Simpson, Thomas J.; Willis, Christine L.; Cox, Russell J.; Bailey, Andrew M. (Cambridge : Royal Society of Chemistry, 2018)
    The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the reported insecticidal activity of the minor metabolite, ...