Auflistung nach Schlagwort "Antibiotics"

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  • Ghai, Ishan; Ghai, Shashank (Macclesfield : Dove Medical Press, 2017)
    One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an effective change in the membrane permeability to antibiotics. The Gram-negative bacterial complex cell envelope comprises ...
  • Ehlert, Nina; Badar, Muhammad; Christel, Anne; Lohmeier, Sven Jare; Luessenhop, Tammo; Stieve, Martin; Lenarz, Thomas; Mueller, Peter Paul; Behrens, Peter (Cambridge : Royal Society of Chemistry, 2011)
    To generate bioactive coatings for medical implants, a novel procedure has been developed using a coating of mesoporous silica for controlled drug delivery. Plain glass slides were used as substrates. The mesoporous coatings ...
  • Harmrolfs, Kirsten; Mancuso, Lena; Drung, Binia; Sasse, Florenz; Kirschning, Andreas (Frankfurt am Main : Beilstein-Institut zur Förderung der Chemischen Wissenschaften, 2014)
    The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a ...
  • Wang, Liang-Liang; Kirschning, Andreas (Frankfurt am Main : Beilstein-Institut zur Förderung der Chemischen Wissenschaften, 2017)
    The elansolids A1–A3, B1, and B2 are secondary metabolites formed by the gliding bacterium Chitinophaga sancti. They show antibacterial activity against Gram-positive bacteria. A second generation total synthesis of the ...
  • Ghai, Ishan; Ghai, Shashank (Macclesfield : Dove Medical Press, 2018)
    Collective antibiotic drug resistance is a global threat, especially with respect to Gram-negative bacteria. The low permeability of the bacterial outer cell wall has been identified as a challenging barrier that prevents ...
  • Knobloch, Tobias; Draeger, Gerald; Collisi, Wera; Sasse, Florenz; Kirschning, Andreas (Frankfurt am Main : Beilstein-Institut Zur Förderung der Chemischen Wissenschaften, 2012)
    We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants ...