Auflistung nach Autor/in "beaff9a1-1c72-4f69-a97d-138d5cd4f836"

Auflistung nach Autor/in "beaff9a1-1c72-4f69-a97d-138d5cd4f836"

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  • Halogenated Rocaglate Derivatives: Pan-antiviral Agents against Hepatitis E Virus and Emerging Viruses 
    Victoria, Catherine; Schulz, Göran; Klöhn, Mara; Weber, Saskia; Holicki, Cora M.; Brüggemann, Yannick; Becker, Miriam; Gerold, Gisa; Eiden, Martin; Groschup, Martin H.; Steinmann, Eike; Kirschning, Andreas (Washington, DC : ACS, 2023)
    The synthesis of a library of halogenated rocaglate derivatives belonging to the flavagline class of natural products, of which silvestrol is the most prominent example, is reported. Their antiviral activity and cytotoxicity ...
  • Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication 
    Praditya, Dimas F.; Klöhn, Mara; Brüggemann, Yannick; Brown, Lauren E.; Porco, John A.; Zhang, Wenhan; Kinast, Volker; Kirschning, Andreas; Vondran, Florian W.R.; Todt, Daniel; Steinmann, Eike (Amsterdam [u.a.] : Elsevier Science, 2022)
    Hepatitis E virus (HEV) infections are a leading cause of acute viral hepatitis in humans and pose a considerable threat to public health. Current standard of care treatment is limited to the off-label use of nucleoside-analog ...