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Auflistung nach Autor/in "24828d19-f391-4bae-8158-23284434fbb1"

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Analysis of SARS-CoV-2 spike RBD binding to ACE2 and its inhibition by fungal cohaerin C using surface enhanced Raman spectroscopy

Wetzel, Christoph; Jansen-Olliges, Linda; Stadler, Marc; Surup, Frank; Zeilinger, Carsten; Roth, Bernhard (Washington, DC : Optica, 2023)

The structure of the SARS-CoV-2 spike RBD and human ACE2 as well as changes in the structure due to binding activities were analysed using surface enhanced Raman spectroscopy. The inhibitor cohaerin C was applied to inhibit ...
Identification of a Thyroid Hormone Binding Site in Hsp90 with Implications for Its Interaction with Thyroid Hormone Receptor Beta

Fan, Lu; Kishore, Anusha; Jansen-Olliges, Linda; Wang, Dahua; Stahl, Frank; Psathaki, Olympia Ekaterini; Harre, Jennifer; Warnecke, Athanasia; Weder, Julia; Preller, Matthias; Zeilinger, Carsten (Washington, DC : ACS Publications, 2022)

While many proteins are known clients of heat shock protein 90 (Hsp90), it is unclear whether the transcription factor, thyroid hormone receptor beta (TRb), interacts with Hsp90 to control hormonal perception and signaling. ...
Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids?

Solga, Danny; Wieske, Lianne H. E.; Wilcox, Scott; Zeilinger, Carsten; Jansen‐Olliges, Linda; Cirnski, Katarina; Herrmann, Jennifer; Müller, Rolf; Erdelyi, Mate; Kirschning, Andreas (Weinheim : Wiley-VCH, 2024)

Cystobactamids are aromatic oligoamides that exert their natural antibacterial properties by inhibition of bacterial gyrases. Such aromatic oligoamides were proposed to inhibit α-helix-mediated protein-protein interactions ...
Multiformin-Type Azaphilones Prevent SARS-CoV-2 Binding to ACE2 Receptor

Jansen-Olliges, Linda; Chatterjee, Shambhabi; Jia, Lili; Stahl, Frank; Bär, Christian; Stadler, Marc; Surup, Frank; Zeilinger, Carsten (Basel : MDPI, 2023)

Protein microarray screenings identified fungal natural products from the azaphilone family as potent inhibitors of SARS-CoV-2 spike protein binding to host ACE2 receptors. Cohaerin F, as the most potent substance from the ...

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Auflistung nach Autor/in "24828d19-f391-4bae-8158-23284434fbb1"

Auflistung nach Autor/in "24828d19-f391-4bae-8158-23284434fbb1"

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