Auflistung nach Autor/in "11fcf772-5cb0-45c6-a360-6e805de1a637"

Auflistung nach Autor/in "11fcf772-5cb0-45c6-a360-6e805de1a637"

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  • CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model 
    Brooks, Pascal; Zur Bruegge, Talke; Boyle, Erin C.; Kalies, Stefan; Villarreal, Santiago Nahuel; Liese, Andrea; Bleich, André; Buettner, Manuela (London : Hindawi Limited, 2020)
    Cd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. CD14 acts as a coreceptor for bacterial lipopolysaccharide (LPS), while ALPK1 ...
  • Epithelial restitution in 3D - Revealing biomechanical and physiochemical dynamics in intestinal organoids via fs laser nanosurgery 
    Donath, Sören; Seidler, Anna Elisabeth; Mundin, Karlina; Wenzel, Johannes; Scholz, Jonas; Gentemann, Lara; Kalies, Julia; Faix, Jan; Ngezahayo, Anaclet; Bleich, André; Heisterkamp, Alexander; Buettner, Manuela; Kalies, Stefan (Amsterdam [u.a.] : Elsevier, 2023)
    Intestinal organoids represent a three-dimensional cell culture system mimicking the mammalian intestine. The application of single-cell ablation for defined wounding via a femtosecond laser system within the crypt base ...
  • Establishment of a guided, in vivo, multi-channel, abdominal, tissue imaging approach 
    Bahlmann, Julia; Madrahimov, Nodir; Daniel, Fiene; Theidel, David; DeTemple, Daphne E.; Buettner, Manuela; Bleich, André; Haverich, Axel; Heisterkamp, Alexander; Kalies, Stefan (London : Nature Publishing Group, 2020)
    Novel tools in humane animal research should benefit the animal as well as the experimentally obtained data. Imaging technologies have proven to be versatile and also in accordance with the demands of the 3 R principle. ...
  • Intestinal Organoids in Colitis Research: Focusing on Variability and Cryopreservation 
    zur Bruegge, Talke F.; Liese, Andrea; Donath, Sören; Kalies, Stefan; Kosanke, Maike; Dittrich-Breiholz, Oliver; Czech, Sandra; Bauer, Verena N.; Bleich, André; Buettner, Manuela (London [u.a.] : Sage-Hindawi, 2021)
    In recent years, stem cell-derived organoids have become a cell culture standard that is widely used for studying various scientific issues that were previously investigated through animal experiments and using common tumor ...
  • Investigation of Colonic Regeneration via Precise Damage Application Using Femtosecond Laser-Based Nanosurgery 
    Donath, Sören; Angerstein, Leon; Gentemann, Lara; Müller, Dominik; Seidler, Anna E.; Jesinghaus, Christian; Bleich, André; Heisterkamp, Alexander; Buettner, Manuela; Kalies, Stefan (Basel : MDPI, 2022)
    Organoids represent the cellular composition of natural tissue. So called colonoids, organoids derived from colon tissue, are a good model for understanding regeneration. However, next to the cellular composition, the ...
  • Mimicking acute airway tissue damage using femtosecond laser nanosurgery in airway organoids 
    Gentemann, Lara; Donath, Sören; Seidler, Anna E.; Patyk, Lara; Buettner, Manuela; Heisterkamp, Alexander; Kalies, Stefan (Lausanne : Frontiers Media, 2023)
    Airway organoids derived from adult murine epithelial cells represent a complex 3D in vitro system mimicking the airway epithelial tissue’s native cell composition and physiological properties. In combination with a precise ...
  • Postoperative Severity Assessment in Sheep 
    Zentrich, Eva; Wassermann, Laura; Struve, Birgitta; Selke, Kristin; Buettner, Manuela; Keubler, Lydia Maria; Reifenrath, Janin; Angrisani, Nina; Kempfert, Merle; Krause, Annika; Bellmann, Olaf; Kopaczka, Marcin; Merhof, Dorit; Bankstahl, Marion; Bleich, André; Häger, Christine (Basel [u.a.] : Karger, 2023)
    Introduction: Sheep are frequently used in translational surgical orthopedic studies. Naturally, a good pain management is mandatory for animal welfare, although it is also important with regard to data quality. However, ...