Seleci, M.; Ag Seleci, D.; Joncyzk, R.; Stahl, F.; Blume, C. et al.: Smart multifunctional nanoparticles in nanomedicine. In: BioNanoMaterials 17 (2016), Nr. Februar, S. 33-41. DOI:
https://doi.org/10.1515/bnm-2015-0030
Zusammenfassung: |
Recent advances in nanotechnology caused a growing interest using nanomaterials in medicine to solve a number of issues associated with therapeutic agents. The fabricated nanomaterials with unique physical and chemical properties have been investigated for both diagnostic and therapeutic applications. Therapeutic agents have been combined with the nanoparticles to minimize systemic toxicity, increase their solubility, prolong the circulation half-life, reduce their immunogenicity and improve their distribution. Multifunctional nanoparticles have shown great promise in targeted imaging and therapy. In this review, we summarized the physical parameters of nanoparticles for construction of "smart" multifunctional nanoparticles and their various surface engineering strategies. Outlook and questions for the further researches were discussed. © 2016 by De Gruyter.
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Lizenzbestimmungen: |
Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. |
Publikationstyp: |
Article |
Publikationsstatus: |
publishedVersion |
Erstveröffentlichung: |
2016 |
Schlagwörter (englisch): |
drug delivery system, medical applications, nanomaterials, nanomedicine, nanoparticles, targeting therapy, drug carrier, ligand, nanocarrier, nanomaterial, nanoparticle, Article, drug delivery system, drug half life, drug release, drug safety, drug solubility, immunogenicity, nanoengineering, nanomedicine, nanotechnology, physical chemistry, priority journal, surface property
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Fachliche Zuordnung (DDC): |
610 | Medizin, Gesundheit
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