dc.identifier.uri |
http://dx.doi.org/10.15488/14371 |
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dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/14488 |
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dc.contributor.author |
Koeder, Christian
|
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dc.contributor.author |
Husain, Sarah
|
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dc.contributor.author |
Kranz, Ragna-Marie
|
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dc.contributor.author |
Anand, Corinna
|
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dc.contributor.author |
Alzughayyar, Dima
|
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dc.contributor.author |
Schoch, Nora
|
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dc.contributor.author |
Hahn, Andreas
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dc.contributor.author |
Englert, Heike
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dc.date.accessioned |
2023-07-31T07:00:10Z |
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dc.date.available |
2023-07-31T07:00:10Z |
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dc.date.issued |
2022 |
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dc.identifier.citation |
Koeder, C.; Husain, S.; Kranz, R.-M.; Anand, C.; Alzughayyar, D. et al.: Healthy lifestyle changes favourably affect common carotid intima-media thickness: the Healthy Lifestyle Community Programme (cohort 2). In: Journal of Nutritional Science 11 (2022), e47. DOI: https://doi.org/10.1017/jns.2022.46 |
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dc.description.abstract |
Common carotid intima-media thickness (ccIMT) progression is a risk marker for cardiovascular disease (CVD), whereas healthy lifestyle habits are associated with lower ccIMT. The objective of the present study was to test whether a healthy lifestyle intervention can beneficially affect ccIMT progression. A community-based non-randomised, controlled lifestyle intervention was conducted, focusing on a predominantly plant-based diet (strongest emphasis), physical activity, stress management and social health. Assessments of ccIMT were made at baseline, 6 months and 1 year. Participants had an average age of 57 years and were recruited from the general population in rural northwest Germany (intervention: n 114; control: n 87). From baseline to 1 year, mean ccIMT significantly increased in both the intervention (0.026 [95 % CI 0.012, 0.039] mm) and control group (0.045 [95 % CI 0.033, 0.056] mm). The 1-year trajectory of mean ccIMT was lower in the intervention group (P = 0.022; adjusted for baseline). In a subgroup analysis with participants with high baseline mean ccIMT (≥0.800 mm), mean ccIMT non-significantly decreased in the intervention group (-0.016 [95 % CI -0.050, 0.017] mm; n 18) and significantly increased in the control group (0.065 [95 % CI 0.033, 0.096] mm; n 12). In the subgroup, the 1-year trajectory of mean ccIMT was significantly lower in the intervention group (between-group difference: -0.051 [95 % CI -0.075, -0.027] mm; P < 0.001; adjusted for baseline). The results indicate that healthy lifestyle changes may beneficially affect ccIMT within 1 year, particularly if baseline ccIMT is high. |
eng |
dc.language.iso |
eng |
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dc.publisher |
Cambridge : Cambridge Univ. Press |
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dc.relation.ispartofseries |
Journal of Nutritional Science 11 (2022) |
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dc.rights |
CC BY 4.0 Unported |
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dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
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dc.subject |
Cardiovascular disease |
eng |
dc.subject |
Cardiovascular health |
eng |
dc.subject |
Cardiovascular prevention |
eng |
dc.subject |
Carotid intima-media thickness |
eng |
dc.subject |
Lifestyle medicine |
eng |
dc.subject |
Plant-based diet |
eng |
dc.subject |
Preventive medicine |
eng |
dc.subject.ddc |
610 | Medizin, Gesundheit
|
|
dc.subject.ddc |
570 | Biowissenschaften, Biologie
|
|
dc.title |
Healthy lifestyle changes favourably affect common carotid intima-media thickness: the Healthy Lifestyle Community Programme (cohort 2) |
eng |
dc.type |
Article |
|
dc.type |
Text |
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dc.relation.essn |
2048-6790 |
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dc.relation.doi |
https://doi.org/10.1017/jns.2022.46 |
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dc.bibliographicCitation.volume |
11 |
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dc.bibliographicCitation.firstPage |
e47 |
|
dc.description.version |
publishedVersion |
eng |
tib.accessRights |
frei zug�nglich |
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dc.bibliographicCitation.articleNumber |
e47 |
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