Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides

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Hemmerling, Franziska; Hahn, Frank: Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides. In: Beilstein Journal of Organic Chemistry 12 (2016), S. 1512-1550. DOI: http://dx.doi.org/10.3762/bjoc.12.148

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Sum total of downloads: 269




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Abstract: 
This review highlights the biosynthesis of heterocycles in polyketide natural products with a focus on oxygen and nitrogen-containing heterocycles with ring sizes between 3 and 6 atoms. Heterocycles are abundant structural elements of natural products from all classes and they often contribute significantly to their biological activity. Progress in recent years has led to a much better understanding of their biosynthesis. In this context, plenty of novel enzymology has been discovered, suggesting that these pathways are an attractive target for future studies.
License of this version: CC BY 2.0 Unported
Document Type: Article
Publishing status: publishedVersion
Issue Date: 2016
Appears in Collections:Naturwissenschaftliche Fakultät

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pos. country downloads
total perc.
1 image of flag of Germany Germany 204 75.84%
2 image of flag of United States United States 26 9.67%
3 image of flag of China China 5 1.86%
4 image of flag of Japan Japan 4 1.49%
5 image of flag of Russian Federation Russian Federation 3 1.12%
6 image of flag of Italy Italy 2 0.74%
7 image of flag of France France 2 0.74%
8 image of flag of Spain Spain 2 0.74%
9 image of flag of Egypt Egypt 2 0.74%
10 image of flag of Chile Chile 2 0.74%
    other countries 17 6.32%

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