Auflistung nach Schlagwort "structural biology"

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  • Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses 
    Napolitano, Valeria; Dabrowska, Agnieszka; Schorpp, Kenji; Mourao, Andre; Barreto-Duran, Emilia; Benedyk, Malgorzata; Botwina, Pawel; Brandner, Stefanie; Bostock, Mark; Chykunova, Yuliya; Czarna, Anna; Dubin, Grzegorz; Froehlich, Tony; Hoelscher, Michael; Jedrysik, Malwina; Matsuda, Alex; Owczarek, Katarzyna; Pachota, Magdalena; Plettenburg, Oliver; Potempa, Jan; Rothenaigner, Ina; Schlauderer, Florian; Slysz, Klaudia; Szczepanski, Artur; Mohn, Kristin Greve-Isdahl; Blomberg, Bjorn; Sattler, Michael; Hadian, Kamyar; Popowicz, Grzegorz Maria; Pyrc, Krzysztof (Amsterdam : Elsevier, 2022)
    The COVID-19 pandemic caused by SARS-CoV-2 has been socially and economically devastating. Despite an unprecedented research effort and available vaccines, effective therapeutics are still missing to limit severe disease ...
  • Dissecting the Mechanism of Protein Unfolding by the Unfoldase PAN using Structural Biology 
    Krüger, Georg Ernst Heinrich (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2021)
    The proteasome as the major cellular protease plays a central role in regulated protein deg-radation in all kingdoms of life. Besides the proteolytic core particle, the proteasome com-prises an ATP-dependent unfoldase ...
  • Structural basis for histone H3 acetylation by Rtt109 in complex with histone chaperones Asf1 and Vps75 
    Danilenko, Nataliya (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2020)
    In eukaryotes, genetic material is stored as chromatin, a DNA-protein complex whose structure is tightly regulated. Histones are the main protein components of chromatin and their post-translational modifications (PTMs) ...
  • Structure of the multi-subunit chloroplast RNA polymerase 
    do Prado, Paula F.V.; Ahrens, Frederik M.; Liebers, Monique; Ditz, Noah; Braun, Hans-Peter; Pfannschmidt, Thomas; Hillen, Hauke S. (New York, NY : Elsevier, 2024)
    Chloroplasts contain a dedicated genome that encodes subunits of the photosynthesis machinery. Transcription of photosynthesis genes is predominantly carried out by a plastid-encoded RNA polymerase (PEP), a nearly 1 MDa ...