Auflistung nach Schlagwort "aspergillus-nidulans"

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  • One pathway, many compounds: heterologous expression of a fungal biosynthetic pathway reveals its intrinsic potential for diversity 
    Wasil, Zahida; Pahirulzaman, Khomaizon A.K.; Butts, Craig; Simpson, Thomas J.; Lazarus, Colin M.; Cox, Russell J. (Cambridge : Royal Society of Chemistry, 2013-08-08)
    Heterologous expression of genes from the proposed aspyridone biosynthetic cluster from Aspergillus nidulans in the host Aspergillus oryzae led to the production of eight different compounds in addition to aspyridone A 1, ...
  • Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis 
    Al-Fahad, Ahmed; Abood, Amira; Fisch, Katja M.; Osipow, Anna; Davison, Jack; Avramovic, Marija; Butts, Craig; Piel, Joern; Simpson, Thomas J.; Cox, Russell J. (Cambridge : Royal Society of Chemistry, 2013-11-20)
    An FAD-dependent monooxygenase encoding gene (SorbC) was cloned from Penicillium chrysogenum E01-10/3 and expressed as a soluble protein in Escherichia coli. The enzyme efficiently performed the oxidative dearomatisation ...
  • Oxidative rearrangements during fungal biosynthesis 
    Cox, Russell J. (Cambridge : Royal Society of Chemistry, 2014-07-25)
    Oxidative rearrangements are key reactions during the biosyntheses of many secondary metabolites in fungi. This review highlights the most important examples of these reactions and aims to draw together key mechanistic ...