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Abdominal obesity‐related disturbance of insulin sensitivity is associated with cd8+ emra cells in the elderly

Boßlau, Tim K.; Wasserfurth, Paulina; Krüger, Britta; Reichel, Thoma; Palmowski, Jana; Nebl, Josefine; Weyh, Christopher; Schenk, Alexander; Joisten, Niklas; Stahl, Frank; Thoms, Stefanie; Gebhardt, Kristina; Hahn, Andreas; Krüger, Karsten (Basel : MDPI, 2021)

Aging and overweight increase the risk of developing type 2 diabetes mellitus. In this cross‐sectional study, we aimed to investigate the potential mediating role of T‐EMRA cells and inflammatory markers in the development ...
Decline of coronary heart disease mortality is strongly effected by changing patterns of underlying causes of death: an analysis of mortality data from 27 countries of the WHO European region 2000 and 2013

Stolpe, Susanne; Kowall, Bernd; Stang, Andreas (Cham : Springer Nature, 2021)

Mortality rates for coronary heart disease (CHD) experience a longstanding decline, attributed to progress in prevention, diagnostics and therapy. However, CHD mortality rates vary between countries. To estimate whether ...
Diet-dependent net endogenous acid load of vegan diets in relation to food groups and bone health-related nutrients: Results from the German Vegan Study

Ströhle, Alexander; Waldmann, Annika; Koschizke, Jochen; Leitzmann, Claus; Hahn, Andreas (Basel : S. Karger AG, 2011)

Background/Aims:Dietary composition has been shown to affect acid-base homeostasis and bone health in humans. We investigated the potential renal acid load (PRAL) and the estimated diet-dependent net acid load (net endogenous ...
Dietary iron intake and iron status of German female vegans: Results of the German Vegan Study

Waldmann, Annika; Koschizke, Jochen W.; Leitzmann, Claus; Hahn, Andreas (Basel : S. Karger AG, 2004)

Background: As shown in previous studies vegetarians and especially vegans are at risk for iron deficiency. Our study evaluated the iron status of German female vegans. Methods: In this cross-sectional study, the dietary ...
Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: Results from a randomized controlled trial

Schmidt, Simone; Stahl, Frank; Mutz, Kai-Oliver; Scheper, Thomas; Hahn, Andreas; Schuchardt, Jan Philipp (London : BioMed Central Ltd., 2012)

Background: Epidemiological studies have suggested the benefits of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cardiovascular health, but only limited data are available describing n-3 PUFA regulated pathways in ...
German vegan study: Diet, life-style factors, and cardiovascular risk profile

Waldmann, A.; Koschizke, J.W.; Leitzmann, C.; Hahn, A. (Basel : S. Karger AG, 2005)

Background/Aim: Evaluation of cardiovascular risk profile in 154 German vegans. Methods: Cross-sectional study, Germany. Study instruments: 2 FFQ, 2 questionnaires, analyses of fasting venous blood samples. Results: The ...
Homocysteine and cobalamin status in German vegans

Waldmann, Annika; Koschizke, Jochen W.; Leitzmann, Claus; Hahn, Andreas (Cambridge : Cambridge University Press, 2004)

Objective: The study aimed to evaluate the homocysteine and cobalamin status of German vegans and determine whether the intake of very small amounts of foods of animal origin can improve this status. Design and setting: ...
Monocyte chemotactic protein-1 as a potential biomarker for early anti-thrombotic therapy after ischemic stroke

Worthmann, Hans; Dengler, Reinhard; Schumacher, Helmut; Schwartz, Andreas; Eisert, Wolfgang G.; Lichtinghagen, Ralf; Weissenborn, Karin (Basel : MDPI AG, 2012)

Inflammation following ischemic brain injury is correlated with adverse outcome. Preclinical studies indicate that treatment with acetylsalicylic acid + extended-release dipyridamole (ASA + ER-DP) has anti-inflammatory and ...
Outcome stagnation of liver transplantation for primary sclerosing cholangitis in the Model for End-Stage Liver Disease era

Klose, Johannes; Klose, Michelle A.; Metz, Courtney; Lehner, Frank; Manns, Michael P.; Klempnauer, Jürgen; Hoppe, Nils; Schrem, Harald; Kaltenborn, Alexander (Heidelberg : Springer Verlag, 2014)

Purpose: Survival after liver transplantation (LTX) has decreased in Germany since the implementation of Model for end-stage liver disease (MELD)-based liver allocation. Primary sclerosing cholangitis (PSC) is known for ...
Overall glycemic index and glycemic load of vegan diets in relation to plasma lipoproteins and triacylglycerols

Waldmann, Annika; Ströhle, Alexander; Koschizke, Jochen W.; Leitzmann, Claus; Hahn, Andreas (Basel : S. Karger AG, 2007)

Background: To investigate the overall glycemic index (GI), glycemic load (GL), and intake of dietary fiber, and to examine the associations between these factors and plasma lipoproteins and triacylglycerols in adult vegans ...
Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients

Wang, Weiwei; Li, Wenzhong; Ou, Lailiang; Flick, Eva; Mark, Peter; Nesselmann, Catharina; Lux, Cornelia A.; Gatzen, Hanz-Heinrich; Kaminski, Alexander; Liebold, Andreas; Lützow, Karola; Lendlein, Andreas; Li, Ren-Ke; Steinhoff, Gustav; Ma, Nan (Chichester : Wiley-Blackwell Publishing Ltd., 2011)

Transplantation of mesenchymal stem cells (MSCs) derived from adult bone marrow has been proposed as a potential therapeutic approach for post-infarction left ventricular (LV) dysfunction. However, age-related functional ...
Regulation of lipid metabolism-related gene expression in whole blood cells of normo- and dyslipidemic men after fish oil supplementation

Schmidt, Simone; Willers, Janina; Stahl, Frank; Mutz, Kai-Oliver; Scheper, Thomas; Hahn, Andreas; Schuchardt, Jan Philipp (London : BioMed Central Ltd., 2012)

Background: Beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on the lipid levels of dyslipidemic subjects are widely described in the literature. However, the underlying molecular mechanisms are largely ...
Relaxing restrictions at the pace of vaccination increases freedom and guards against further COVID-19 waves

Bauer, Simon; Contreras, Sebastian; Dehning, Jonas; Linden, Matthias; Iftekhar, Emil; Mohr, Sebastian B.; Olivera-Nappa, Alvaro; Priesemann, Viola (San Francisco, Calif. : Public Library of Science, 2021)

Mass vaccination offers a promising exit strategy for the COVID-19 pandemic. However, as vaccination progresses, demands to lift restrictions increase, despite most of the population remaining susceptible. Using our ...
The socioeconomic profile of patients treated by phlebotropic drugs in Germany

Uber, Andrea (London : SAGE Publications Ltd., 1997)

Conservative treatment of venous disease is difficult. There is much skepticism concerning the efficacy of drugs in venous diseases. Nevertheless, in Germany, these drugs have obtained a substantial market share with a ...
Telemonitoring-Supported Exercise Training in Employees With Metabolic Syndrome Improves Liver Inflammation and Fibrosis

Haufe, Sven; Hupa-Breier, Katharina L.; Bayerle, Pauline; Boeck, Hedwig T.; Rolff, Simone; Sundermeier, Thorben; Kerling, Arno; Eigendorf, Julian; Kück, Momme; Hanke, Alexander A.; Ensslen, Ralf; Nachbar, Lars; Lauenstein, Dirk; Böthig, Dietmar; Hilfiker-Kleiner, Denise; Stiesch, Meike; Terkamp, Christoph; Wedemeyer, Heiner; Haverich, Axel; Tegtbur, Uwe (London : Nature Publ. Group, 2021)

INTRODUCTION:Metabolic syndrome (MetS) is a major health problem worldwide and the main risk factor for metabolic-associated fatty liver disease (MAFLD). Established treatment options are lifestyle interventions facilitating ...

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