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Browsing by Subject "middle aged"

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Abdominal obesity‐related disturbance of insulin sensitivity is associated with cd8+ emra cells in the elderly

Boßlau, Tim K.; Wasserfurth, Paulina; Krüger, Britta; Reichel, Thoma; Palmowski, Jana; Nebl, Josefine; Weyh, Christopher; Schenk, Alexander; Joisten, Niklas; Stahl, Frank; Thoms, Stefanie; Gebhardt, Kristina; Hahn, Andreas; Krüger, Karsten (Basel : MDPI, 2021)

Aging and overweight increase the risk of developing type 2 diabetes mellitus. In this cross‐sectional study, we aimed to investigate the potential mediating role of T‐EMRA cells and inflammatory markers in the development ...
Decline of coronary heart disease mortality is strongly effected by changing patterns of underlying causes of death: an analysis of mortality data from 27 countries of the WHO European region 2000 and 2013

Stolpe, Susanne; Kowall, Bernd; Stang, Andreas (Cham : Springer Nature, 2021)

Mortality rates for coronary heart disease (CHD) experience a longstanding decline, attributed to progress in prevention, diagnostics and therapy. However, CHD mortality rates vary between countries. To estimate whether ...
High unawareness of chronic kidney disease in Germany

Stolpe, Susanne; Kowall, Bernd; Scholz, Christian; Stang, Andreas; Blume, Cornelia (Basel : MDPI, 2021)

Chronic kidney disease (CKD) is associated with an increased risk for cardiovascular events, hospitalizations, end stage renal disease and mortality. Main risk factors for CKD are diabetes, hypertension, and older age. ...
Homocysteine and cobalamin status in German vegans

Waldmann, Annika; Koschizke, Jochen W.; Leitzmann, Claus; Hahn, Andreas (Cambridge : Cambridge University Press, 2004)

Objective: The study aimed to evaluate the homocysteine and cobalamin status of German vegans and determine whether the intake of very small amounts of foods of animal origin can improve this status. Design and setting: ...
Monocyte chemotactic protein-1 as a potential biomarker for early anti-thrombotic therapy after ischemic stroke

Worthmann, Hans; Dengler, Reinhard; Schumacher, Helmut; Schwartz, Andreas; Eisert, Wolfgang G.; Lichtinghagen, Ralf; Weissenborn, Karin (Basel : MDPI AG, 2012)

Inflammation following ischemic brain injury is correlated with adverse outcome. Preclinical studies indicate that treatment with acetylsalicylic acid + extended-release dipyridamole (ASA + ER-DP) has anti-inflammatory and ...
Outcome stagnation of liver transplantation for primary sclerosing cholangitis in the Model for End-Stage Liver Disease era

Klose, Johannes; Klose, Michelle A.; Metz, Courtney; Lehner, Frank; Manns, Michael P.; Klempnauer, Jürgen; Hoppe, Nils; Schrem, Harald; Kaltenborn, Alexander (Heidelberg : Springer Verlag, 2014)

Purpose: Survival after liver transplantation (LTX) has decreased in Germany since the implementation of Model for end-stage liver disease (MELD)-based liver allocation. Primary sclerosing cholangitis (PSC) is known for ...
Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients

Wang, Weiwei; Li, Wenzhong; Ou, Lailiang; Flick, Eva; Mark, Peter; Nesselmann, Catharina; Lux, Cornelia A.; Gatzen, Hanz-Heinrich; Kaminski, Alexander; Liebold, Andreas; Lützow, Karola; Lendlein, Andreas; Li, Ren-Ke; Steinhoff, Gustav; Ma, Nan (Chichester : Wiley-Blackwell Publishing Ltd., 2011)

Transplantation of mesenchymal stem cells (MSCs) derived from adult bone marrow has been proposed as a potential therapeutic approach for post-infarction left ventricular (LV) dysfunction. However, age-related functional ...
Telemonitoring-Supported Exercise Training in Employees With Metabolic Syndrome Improves Liver Inflammation and Fibrosis

Haufe, Sven; Hupa-Breier, Katharina L.; Bayerle, Pauline; Boeck, Hedwig T.; Rolff, Simone; Sundermeier, Thorben; Kerling, Arno; Eigendorf, Julian; Kück, Momme; Hanke, Alexander A.; Ensslen, Ralf; Nachbar, Lars; Lauenstein, Dirk; Böthig, Dietmar; Hilfiker-Kleiner, Denise; Stiesch, Meike; Terkamp, Christoph; Wedemeyer, Heiner; Haverich, Axel; Tegtbur, Uwe (London : Nature Publ. Group, 2021)

INTRODUCTION:Metabolic syndrome (MetS) is a major health problem worldwide and the main risk factor for metabolic-associated fatty liver disease (MAFLD). Established treatment options are lifestyle interventions facilitating ...

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