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First-in-class positron emission tomography tracer for the glucagon receptor

Velikyan, Irina; Haack, Torsten; Bossart, Martin; Evers, Andreas; Laitinen, Ilina; Larsen, Philip; Plettenburg, Oliver; Johansson, Lars; Pierrou, Stefan; Wagner, Michael; Eriksson, Olof (Heidelberg : Springer Verlag, 2019)

Abstract: The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially as part of the pharmacology of dual glucagon-like peptide-1/glucagon (GLP-1/GCG) receptor agonists. However, ...
Forces and trauma associated with minimally invasive image-guided cochlear implantation

Rohani, Pooyan; Pile, Jason; Kahrs, Lüder Alexander; Balachandran, Ramya; Blachon, Gregoire S.; Simaan, Nabil; Labadie, Robert F. (London : SAGE Publications Ltd., 2014)

Objective. Minimally invasive image-guided cochlear implantation (CI) utilizes a patient-customized microstereotactic frame to access the cochlea via a single drill-pass. We investigate the average force and trauma associated ...
High intensity high volume interval training improves endurance performance and induces a nearly complete slow-to-fast fiber transformation on the mRNA level

Eigendorf, Julian; May, Marcus; Friedrich, Jan; Engeli, Stefan; Maassen, Norbert; Gros, Gerolf; Meissner, Joachim D. (Lausanne : Frontiers Media S.A., 2018)

We present here a longitudinal study determining the effects of two 3 week-periods of high intensity high volume interval training (HIHVT) (90 intervals of 6 s cycling at 250% maximum power, Pmax/24 s) on a cycle ergometer. ...

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