Mazurenka, M.; Behrendt, L.; Meinhardt-Wollweber, M.; Morgner, U.; Roth, B.: Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening. In: Review of Scientific Instruments 88 (2017), Nr. 10, 105103. DOI:
https://doi.org/10.1063/1.5004999
Zusammenfassung: |
A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening. © 2017 Author(s).
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Lizenzbestimmungen: |
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Publikationstyp: |
Article |
Publikationsstatus: |
publishedVersion |
Erstveröffentlichung: |
2017 |
Schlagwörter (englisch): |
Dermatology, Diseases, Probes, Clinical application, Combined probes, Fiber bundles, Field of views, Free space optics, Maximum permissible exposure, Skin cancers, Spectral domain OCT, Optical tomography, diagnostic imaging, early cancer diagnosis, human, melanoma, optical coherence tomography, skin tumor, Early Detection of Cancer, Humans, Melanoma, Skin Neoplasms, Tomography, Optical Coherence
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Fachliche Zuordnung (DDC): |
530 | Physik
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