dc.identifier.uri |
http://dx.doi.org/10.15488/108 |
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dc.identifier.uri |
http://www.repo.uni-hannover.de/handle/123456789/126 |
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dc.contributor.author |
Ulusoy, Mehriban
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dc.contributor.author |
Walter, Johanna-Gabriela
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dc.contributor.author |
Lavrentieva, Antonina
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dc.contributor.author |
Kretschmer, Imme
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dc.contributor.author |
Sandiford, Lydia
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dc.contributor.author |
Le Marois, Alix
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dc.contributor.author |
Bongartz, Rebecca
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dc.contributor.author |
Aliuos, Pooyan
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dc.contributor.author |
Suhling, Klaus
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dc.contributor.author |
Stahl, Frank
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dc.contributor.author |
Green, Mark
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dc.contributor.author |
Scheper, Thomas
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dc.date.accessioned |
2015-11-19T12:59:54Z |
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dc.date.available |
2015-12-22T23:05:27Z |
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dc.date.issued |
2014-12-22 |
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dc.identifier.citation |
Ulusoy, Mehriban; Walter, Johanna-Gabriela; Lavrentieva, Antonina; Kretschmer, Imme; Sandiford, Lydia; Le Marois, Alix; Scheper, Thomas et al.: One-pot aqueous synthesis of highly strained CdTe/CdS/ZnS nanocrystals and their interactions with cells. In: RSC Advances 5 (10), S. 7485-7494. DOI: http://dx.doi.org/10.1039/c4ra13386b |
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dc.description.abstract |
In this work, a very simple one-pot synthetic approach was developed to generate aqueous CdTe/CdS/ZnS type-II/type-I red-emitting nanocrystals (NCs). Strain-induced optical properties of CdTe/CdS particles having core((small))/shell((thick)) structure with a maximum quantum yield (QY(max)) similar to 57% were further improved with the overgrowth of a ZnS shell, resulting in a core((small))/shell((thick))/shell((small)) structure (QY(max) similar to 64%). The spectral properties were tuned further to the near-infrared region as the ZnS shell grew in thickness. X-ray powder diffraction (XRD) analysis and high-resolution transmission electron microscope (HRTEM) images showed the crystalline structure of NCs proving the epitaxial growth of ZnS without crystalline defects. Under continuous UV-irradiation for 5 h, the NCs did not exhibit any photo-degradation but instead displayed a photo-annealing process. These extremely photostable NCs were further characterized in terms of their cytotoxicity and their cell labeling performances. The presence of a ZnS shell was found to reduce the toxicity of the CdTe/CdS NCs. Furthermore, aptamer-conjugated NCs were successfully utilized in targeted cell imaging. Promisingly, the aptamer-NCs bioconjugates were internalized by A549 cells within 2 hours of incubation and retained their fluorescence even after 24 hours of internalization. |
eng |
dc.description.sponsorship |
DAAD |
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dc.language.iso |
eng |
eng |
dc.publisher |
Cambridge : Royal Society of Chemistry |
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dc.relation.ispartofseries |
RSC Advances 5 (2015), Nr. 10 |
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dc.rights |
Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. |
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dc.subject |
Shell Quantum Dots |
eng |
dc.subject |
Semiconductor Nanocrystals |
eng |
dc.subject |
Energy-Transfer |
eng |
dc.subject |
Aptamers |
eng |
dc.subject |
Nanoparticles |
eng |
dc.subject |
Phase |
eng |
dc.subject |
Fluorescence |
eng |
dc.subject |
Growth |
eng |
dc.subject.ddc |
540 | Chemie
|
ger |
dc.title |
One-pot aqueous synthesis of highly strained CdTe/CdS/ZnS nanocrystals and their interactions with cells |
eng |
dc.type |
Article |
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dc.type |
Text |
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dc.relation.issn |
2046-2069 |
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dc.relation.doi |
http://dx.doi.org/10.1039/c4ra13386b |
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dc.bibliographicCitation.issue |
10 |
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dc.bibliographicCitation.volume |
5 |
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dc.bibliographicCitation.firstPage |
7485 |
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dc.bibliographicCitation.lastPage |
7494 |
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dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
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