This work presents an extension of graph-based SLAM methods to exploit the potential of 3D laser scans for loop detection. Every high-dimensional point cloud is replaced by a compact global descriptor, whereby a trained detector decides whether a loop exists. Searching for loops is performed locally in a variable space to consider the odometry drift. Since closing a wrong loop has fatal consequences, an extensive verification is performed before acceptance. The proposed algorithm is implemented as an extension of the widely used state-of-the-art library RTAB-Map, and several experiments show the improvement: During SLAM with a mobile service robot in changing indoor and outdoor campus environments, our approach improves RTABMap regarding total number of closed loops. Especially in the presence of significant environmental changes, which typically lead to failure, localization becomes possible by our extension. Experiments with a car in traffic (KITTI benchmark) show the general applicability of our approach. These results are comparable to the state-of-the-art LiDAR method LOAM. The developed ROS package is freely available.© 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.