Auflistung nach Schlagwort "polyketide"

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  • Minimum Information about a Biosynthetic Gene cluster 
    Medema, Marnix H.; Kottmann, Renzo; Yilmaz, Pelin; Cummings, Matthew; Biggins, John B.; Cox, Russell J.; et al. (London : Nature Publishing Group, 2015)
    A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is ...
  • Reductive Release from a Hybrid PKS-NRPS during the Biosynthesis of Pyrichalasin H 
    Heinemann, Henrike; Zhang, Haili; Cox, Russell J. (Weinheim : Wiley-VCH, 2023)
    Three central steps during the biosynthesis of cytochalasan precursors, including reductive release, Knoevenagel cyclisation and Diels Alder cyclisation are not yet understood at a detailed molecular level. In this work ...
  • Understanding and Exploiting the Fungal Biosynthesis of Bisorbicillinoids and Terrein 
    Kahlert, Lukas (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2021)
    The biosynthetic pathways towards the polyketides terrein and (dimeric) sorbicillinoids, such as the Diels-Alder derived bisorbicillinol, were investigated. Both pathways were reconstituted step by step in Aspergillus ...