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3D in vitro platform produced by two-photon polymerization for the analysis of neural network formation and function

Timashev, P.S.; Vedunova, M.V.; Guseva, D.; Ponimaskin, E.; Deiwick, A.; Mishchenko, T.A.; Mitroshina, E.V.; Koroleva, A.V.; Pimashkin, A.S.; Mukhina, I.V.; Panchenko, V.Y.; Chichkov, Boris; Bagratashvili, Victor N. (Bristol : Institute of Physics Publishing, 2016)

Zr-Si organic-inorganic scaffolds fabricated by a two-photon polymerization technique were used for the primary culture of mouse embryonic neural cells. We observed that dissociated hippocampal cells adhere to the scaffolds, ...
A novel shape memory plate osteosynthesis for noninvasive modulation of fixation stiffness in a rabbit tibia osteotomy model

Müller, Christian W.; Pfeifer, Ronny; Meier, Karen; Decker, Sebastian; Reifenrath, Janin; Gösling, Thomas; Wesling, Volker; Krettek, Christian; Hurschler, Christof; Krämer, Manuel (New York, NY : Hindawi Publishing Corporation, 2015)

Nickel-titanium shape memory alloy (NiTi-SMA) implants might allow modulating fracture healing, changing their stiffness through alteration of both elastic modulus and cross-sectional shape by employing the shape memory ...
Adhesion, Vitality and Osteogenic Differentiation Capacity of Adipose Derived Stem Cells Seeded on Nitinol Nanoparticle Coatings

Strauß, Sarah; Neumeister, Anne; Barcikowski, Stephan; Kracht, Dietmar; Kuhbier, Jörn W.; Radtke, Christine; Reimers, Kerstin; Vogt, Peter M. (San Francisco, California, US : PLOS, 2013)

Autologous cells can be used for a bioactivation of osteoimplants to enhance osseointegration. In this regard, adipose derived stem cells (ASCs) offer interesting perspectives in implantology because they are fast and easy ...
AFLP-based genetic mapping of the " bud-flowering" trait in heather (Calluna vulgaris)

Behrend, Anne; Borchert, Thomas; Spiller, Monika; Hohe, Annette (London : BioMed Central Ltd., 2013)

Background: Calluna vulgaris is one of the most important landscaping plants produced in Germany. Its enormous economic success is due to the prolonged flower attractiveness of mutants in flower morphology, the so-called ...
An unusual overrepresentation of genetic factors related to iron homeostasis in the genome of the fluorescent Pseudomonas sp. ABC1

Valenzuela-Heredia, Daniel; Henríquez-Castillo, Carlos; Donoso, Raúl; Lavín, Paris; Ringel, Michael T.; Brüser, Thomas; Campos, José Luis (Oxford : Wiley-Blackwell, 2021)

Members of the genus Pseudomonas inhabit diverse environments, such as soil, water, plants and humans. The variability of habitats is reflected in the diversity of the structure and composition of their genomes. This ...
Biodegradation of a magnesium alloy implant in the intercondylar femoral notch showed an appropriate response to the synovial membrane in a rabbit model in vivo

Ezechieli, Marco; Diekmann, Julia; Weizbauer, Andreas; Becher, Christoph; Willbold, Elmar; Helmecke, Patrick; Lucas, Arne; Schavan, Robert; Windhagen, Henning (London : SAGE Publications Ltd., 2014)

Degradable magnesium alloys are promising biomaterials for orthopedic applications. The aim of this study was to evaluate the potential effects on both the synovial membrane (synovialis) and the synovial fluid (synovia) ...
Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics

Janßen, Hilke Catherina; Angrisani, Nina; Kalies, Stefan; Hansmann, Florian; Kietzmann, Manfred; Warwas, Dawid Peter; Behrens, Peter; Reifenrath, Janin (London : BioMed Central Ltd., 2020)

Background: In orthopedics, the treatment of implant-associated infections represents a high challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved by the use of high doses of antibiotics, ...
Biofunctional quantum dots as fluorescence probe for cell-specific targeting

Ag, Didem; Bongartz, Rebecca; Dogan, Leyla Eral; Seleci, Muharrem; Walter, Johanna-Gabriela; Demirkol, Dilek Odaci; Stahl, Frank; Ozcelik, Serdar; Timur, Suna; Scheper, Thomas (Amsterdam : Elsevier, 2014)

We describe here the synthesis, characterization, bioconjugation, and application of water-soluble thioglycolic acid TGA-capped CdTe/CdS quantum dots (TGA-QDs) for targeted cellular imaging. Anti-human epidermal growth ...
Blue native DIGE as a tool for comparative analyses of protein complexes

Heinemeyer, Jesco; Scheibe, Burghardt; Schmitz, Udo K.; Braun, Hans-Peter (New York, NY [u.a.] : Elsevier, 2009)

Differential gel electrophoresis (DIGE) is based on pre-labeling of different protein fractions and their subsequent co-electrophoresis in a single gel. Cyanine based "CyDye DIGE Fluor minimal dyes" are used for the labeling ...
Burkholderiaceae Are Key Acetate Assimilators During Complete Denitrification in Acidic Cryoturbated Peat Circles of the Arctic Tundra

Hetz, Stefanie A.; Horn, Marcus A. (Lausanne : Frontiers Media, 2021)

Cryoturbated peat circles (pH 4) in the Eastern European Tundra harbor up to 2 mM pore water nitrate and emit the greenhouse gas N2O like heavily fertilized agricultural soils in temperate regions. The main process yielding ...
Carbonic anhydrase subunits form a matrix-exposed domain attached to the membrane arm of mitochondrial complex I in plants

Sunderhaus, Stephanie; Dudkina, Natalya V.; Jänsch, Lothar; Klodmann, Jennifer; Heinemeyer, Jesco; Perales, Mariano; Zabaleta, Eduardo; Boekema, Egbert J.; Braun, Hans-Peter (Bethesda, Md. : ASBMB Publications, 2006)

Complex I of Arabidopsis includes five structurally related subunits representing γ-type carbonic anhydrases termed CA1, CA2, CA3, CAL1, and CAL2. The position of these subunits within complex I was investigated. Direct ...
CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model

Brooks, Pascal; Zur Bruegge, Talke; Boyle, Erin C.; Kalies, Stefan; Villarreal, Santiago Nahuel; Liese, Andrea; Bleich, André; Buettner, Manuela (London : Hindawi Limited, 2020)

Cd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. CD14 acts as a coreceptor for bacterial lipopolysaccharide (LPS), while ALPK1 ...
Co-transfection of plasmid DNA and laser-generated gold nanoparticles does not disturb the bioactivity of GFP-HMGB1 fusion protein

Petersen, Svea; Soller, Jan T.; Wagner, Siegfried; Richter, Andreas; Bullerdiek, Jörn; Nolte, Ingo; Barcikowski, Stephan; Murua Escobar, Hugo (London : Biomed Central, 2009)

Ultrashort pulsed laser ablation in liquids represents a powerful tool for the generation of pure gold nanoparticles (AuNPs) avoiding chemical precursors and thereby making them especially interesting for biomedical ...
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

Hartleben, Goetz; Schorpp, Kenji; Kwon, Yun; Betz, Barbara; Tsokanos, Foivos-Filippos; Dantes, Zahra; Schäfer, Arlett; Rothenaigner, Ina; Monroy Kuhn, José Manuel; Morigny, Pauline; Mehr, Lisa; Lin, Sean; Seitz, Susanne; Tokarz, Janina; Artati, Anna; Adamsky, Jerzy; Plettenburg, Oliver; Lutter, Dominik; Irmler, Martin; Beckers, Johannes; Reichert, Maximilian; Hadian, Kamyar; Zeigerer, Anja; Herzig, Stephan; Berriel Diaz, Mauricio (Weinheim : Wiley-VCH, 2021)

By accentuating drug efficacy and impeding resistance mechanisms, combinatorial, multi-agent therapies have emerged as key approaches in the treatment of complex diseases, most notably cancer. Using high-throughput drug ...
Comparison of nanoparticle-mediated transfection methods for DNA expression plasmids: Efficiency and cytotoxicity

Durán, Maria Carolina; Willenbrock, Saskia; Barchanski, Annette; Müller, Jessika-M.V.; Maiolini, Arianna; Soller, Jan T.; Barcikowski, Stephan; Nolte, Ingo; Feige, Karsten; Murua Escobar, Hugo (London : Biomed Central, 2011)

Background: Reproducibly high transfection rates with low methodology-induced cytotoxic side effects are essential to attain the required effect on targeted cells when exogenous DNA is transfected. Different approaches and ...
Comparison of two prototypes of a magnetically adjustable glaucoma implant in rabbits

Schwerk, Birthe; Harder, Lisa; Windhövel, Claudia; Hewicker-Trautwein, Marion; Wagner, Anna; Bach, Jan-Peter; Voigt, Lena Carolin; Hinze, Ulf; Chichkov, Boris; Haferkamp, Heinz; Lubatschowski, Holger; Nikolic, Stephan; Nolte, Ingo (San Francisco, CA : Public Library of Science (PLoS), 2019)

Glaucoma drainage devices are used in surgical glaucoma therapy. Success of controlling the intraocular pressure is limited due to fibrous implant encapsulation and fibrin coating on the implant which lead to drainage ...
Complexome profiling reveals association of PPR proteins with ribosomes in the mitochondria of plants

Rugen, Nils; Straube, Henryk; Franken, Linda E.; Braun, Hans-Peter; Eubel, Holger (Bethesda, Md. : The American Society for Biochemistry and Molecular Biology, 2019)

Mitochondrial transcripts are subject to a wealth of processing mechanisms including cis- and trans-splicing events, as well as base modifications (RNA editing). HUndreds of proteins are required for these processes in ...
Continuous optical in-line glucose monitoring and control in CHO cultures contributes to enhanced metabolic efficiency while maintaining darbepoetin alfa product quality

Lederle, Mario; Tric, Mircea; Roth, Tatjana; Schütte, Lina; Rattenholl, Anke; Lütkemeyer, Dirk; Wölfl, Stefan; Werner, Tobias; Wiedemann, Philipp (Weinheim : Wiley-VCH, 2021)

Great efforts are directed towards improving productivity, consistency and quality of biopharmaceutical processes and products. One particular area is the development of new sensors for continuous monitoring of critical ...
Crowd of oz : A crowd-powered social robotics system for stress management

Abbas, Tahir; Khan, Vassilis Javed; Gadiraju, Ujwal; Barakova, Emilia; Markopoulos, Panos (Basel : MDPI AG, 2020)

Coping with stress is crucial for a healthy lifestyle. In the past, a great deal of research has been conducted to use socially assistive robots as a therapy to alleviate stress and anxiety related problems. However, ...
Dengue-specific subviral nanoparticles: Design, creation and characterization

Khetarpal, Niyati; Poddar, Ankur; Nemani, Satish K.; Dhar, Nisha; Patil, Aravind; Negi, Priyanka; Perween, Ashiya; Viswanathan, Ramaswamy; Lünsdorf, Heinrich; Tyagi, Poornima; Raut, Rajendra; Arora, Upsana; Jain, Swatantra K.; Rinas, Ursula; Swaminathan, Sathyamangalam; Khanna, Navin (London : BioMed Central Ltd., 2013)

Background: Dengue is today the most significant of arboviral diseases. Novel tools are necessary to effectively address the problem of dengue. Virus-like particles (VLP) offer a versatile nanoscale platform for developing ...

Now showing items 1-20 of 97

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