Auflistung nach Schlagwort "chaperone"

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  • Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa 
    Borgert, Sebastian Roman; Henke, Steffi; Witzgall, Florian; Schmelz, Stefan; zur Lage, Susanne; Hotop, Sven-Kevin; Stephen, Steffi; Lübken, Dennis; Krüger, Jonas; Gomez, Nicolas Oswaldo; van Ham, Marco; Jänsch, Lothar; Kalesse, Markus; Pich, Andreas; Brönstrup, Mark; Häussler, Susanne; Blankenfeldt, Wulf ([London] : Nature Publishing Group UK, 2022)
    Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence ...
  • Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control 
    Carroni, Marta; Franke, Kamila B.; Maurer, Michael; Jäger, Jasmin; Hantke, Ingo; Gloge, Felix; Linder, Daniela; Gremer, Sebastian; Turgay, Kürsad; Bukau, Bernd; Mogk, Axel (Cambridge : eLife Sciences Publications, 2017)
    Ring-forming AAA+ chaperones exert ATP-fueled substrate unfolding by threading through a central pore. This activity is potentially harmful requiring mechanisms for tight repression and substrate-specific activation. The ...
  • Side effects of chaperone gene co-expression in recombinant protein production 
    Martínez-Alonso, Monica; García-Fruitós, Elena; Ferrer-Miralles, Neus; Rinas, Ursula; Villaverde, Antonio (London : BioMed Central Ltd., 2010)
    Insufficient availability of molecular chaperones is observed as a major bottleneck for proper protein folding in recombinant protein production. Therefore, co-production of selected sets of cell chaperones along with ...
  • Xenogeneic modulation of the ClpCP protease of Bacillus subtilis by a phage-encoded adaptor-like protein 
    Mulvenna, N.; Hantke, I.; Burchell, L.; Nicod, S.; Bell, D.; Turgay, K.; Wigneshweraraj, S. (Rockville, MD : American Society for Biochemistry and Molecular Biology Inc., 2019)
    Like eukaryotic and archaeal viruses, which coopt the host's cellular pathways for their replication, bacteriophages have evolved strategies to alter the metabolism of their bacterial host. SPO1 bacteriophage infection of ...