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Auflistung nach Schlagwort "Biocompatibility"

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3D-printed individual labware in biosciences by rapid prototyping: In vitro biocompatibility and applications for eukaryotic cell cultures

Lücking, Tim H.; Sambale, Franziska; Schnaars, Birte; Bulnes-Abundis, David; Beutel, Sascha; Scheper, Thomas (Weinheim : Wiley-VCH Verlag, 2014)

Three-dimensional (3D) printing techniques are continuously evolving, thus their application fields are also growing very fast. The applications discussed here highlight the use of rapid prototyping in a dedicated biotechnology ...
Biocompatibility and degradation of the open-pored magnesium scaffolds LAE442 and La2

Kleer-Reiter, N.; Julmi, S.; Feichtner, F.; Waselau, A.-C.; Klose, C.; Wriggers, P.; Maier, H.J.; Meyer-Lindenberg, A. (London : Inst. of Physics, 2021)

Porous magnesium implants are of particular interest for application as resorbable bone substitutes, due to their mechanical strength and a Young’s modulus similar to bone. The objective of the present study was to compare ...
Biodegradation of a magnesium alloy implant in the intercondylar femoral notch showed an appropriate response to the synovial membrane in a rabbit model in vivo

Ezechieli, Marco; Diekmann, Julia; Weizbauer, Andreas; Becher, Christoph; Willbold, Elmar; Helmecke, Patrick; Lucas, Arne; Schavan, Robert; Windhagen, Henning (London : SAGE Publications Ltd., 2014)

Degradable magnesium alloys are promising biomaterials for orthopedic applications. The aim of this study was to evaluate the potential effects on both the synovial membrane (synovialis) and the synovial fluid (synovia) ...
Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics

Janßen, Hilke Catherina; Angrisani, Nina; Kalies, Stefan; Hansmann, Florian; Kietzmann, Manfred; Warwas, Dawid Peter; Behrens, Peter; Reifenrath, Janin (London : BioMed Central Ltd., 2020)

Background: In orthopedics, the treatment of implant-associated infections represents a high challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved by the use of high doses of antibiotics, ...
Characterization of a customized 3D-printed cell culture system using clear, translucent acrylate that enables optical online monitoring

Siller, Ina Gerhild; Enders, Anton; Gellermann, Pia; Winkler, Steffen; Lavrentieva, Antonina; Scheper, Thomas; Bahnemann, Janina (Bristol : Institute of Physics Publishing, 2020)

Cells are very sensitive to their direct environment - they place high demands, for example, on ambient culture medium, adjacent cell types, and the properties of surrounding material parts. As a result, mechanical and ...
Corrosion fatigue behavior of electron beam melted iron in simulated body fluid

Wackenrohr, Steffen; Torrent, Christof Johannes Jaime; Herbst, Sebastian; Nürnberger, Florian; Krooss, Philipp; Ebbert, Christoph; Voigt, Markus; Grundmeier, Guido; Niendorf, Thomas; Maier, Hans Jürgen ([London] : Macmillan Publishers Limited, part of Springer Nature, 2022)

Pure iron is very attractive as a biodegradable implant material due to its high biocompatibility. In combination with additive manufacturing, which facilitates great flexibility of the implant design, it is possible to ...
Dexamethasone for inner ear therapy: Biocompatibility and bio-efficacy of different dexamethasone formulations in vitro

Gao, Ziwen; Schwieger, Jana; Matin-Mann, Farnaz; Behrens, Peter; Lenarz, Thomas; Scheper, Verena (Basel : MDPI, 2021)

Dexamethasone is widely used in preclinical studies and clinical trials to treat inner ear disorders. The results of those studies vary widely, maybe due to the different dexamethasone formulations used. Laboratory (lab) ...
Evaluation of the biological tolerability of the starch-based medical device 4DryField® PH in vitro and in vivo a rat model

Poehnert, Daniel; Abbas, Mahmoud; Maegel, Lavinia; Sambale, Franziska; Lavrentieva, Antonina; Kreipe, Hans-Heinrich; Klempnauer, Jürgen; Winny, Markus (London : SAGE Publications Ltd., 2015)

Purpose To evaluate in vitro cytotoxicity/biocompatibility as well as in vivo tolerability of the novel polysaccharide 4DryField® PH, certified for haemostasis and adhesion prevention. Methods In vitro cytotoxicity/viability ...
Evaluation of the soft tissue biocompatibility of MgCa0.8 and surgical steel 316L in vivo: A comparative study in rabbits

Erdmann, Nina; Bondarenko, Alexandr; Hewicker-Trautwein, Marion; Angrisani, Nina; Reifenrath, Janin; Lucas, Arne; Meyer-Lindenberg, Andrea (London : BioMed Central Ltd., 2010)

Background: Recent studies have shown the potential suitability of magnesium alloys as biodegradable implants. The aim of the present study was to compare the soft tissue biocompatibility of MgCa0.8 and commonly used ...
Fabrication of a monolithic lab-on-a-chip platform with integrated hydrogel waveguides for chemical sensing

Torres-Mapa, Maria Leilani; Singh, Manmeet; Simon, Olga; Mapa, Jose Louise; Machida, Manan; Günther, Axel; Roth, Bernhard; Heinemann, Dag; Terakawa, Mitsuhiro; Heisterkamp, Alexander (Basel : MDPI AG, 2019)

Hydrogel waveguides have found increased use for variety of applications where biocompatibility and flexibility are important. In this work, we demonstrate the use of polyethylene glycol diacrylate (PEGDA) waveguides to ...
Free Bioverit® II implants coated with a nanoporous silica layer in a mouse ear model - A histological study

Vogt, Julia C.; Brandes, Gudrun; Ehlert, Nina; Behrens, Peter; Nolte, Ingo; Mueller, Peter P.; Lenarz, Thomas; Stieve, Martin (London : SAGE Publications Ltd., 2009)

The objective of this study is to evaluate the suitability of a mouse middle ear model for testing ossicular replacement materials. Twenty-four BALB/c mice are implanted with the bioglass-ceramic Bioverit® II which is ...
Hydrogels for efficient light delivery in optogenetic applications

Johannsmeier, S.; Torres, M.L.; Ripken, T.; Heinemann, D.; Heisterkamp, Alexander (Bellingham, WA : SPIE - International Society for Optical Engineering, 2018)

Light-based therapies have been established for various indications, such as skin conditions, cancer or neonatal jaundice. Advances in the field of optogenetics open up new horizons for light-tissue interactions with an ...
Hydrogels for targeted waveguiding and light diffusion

Johannsmeier, Sonja; Torres-Mapa, Maria L.; Dipresa, Daniele; Ripken, Tammo; Heinemann, Dag; Heisterkamp, Alexander (Washington, DC : OSA - The Optical Society, 2019)

Advances in photomedicine and optogenetics have defined the problem of efficient light delivery in vivo. Recently, hydrogels have been proposed as alternatives to glass or polymer fibers. These materials provide remarkable ...
In vitro and in vivo accumulation of magnetic nanoporous silica nanoparticles on implant materials with different magnetic properties

Janßen, Hilke Catherina; Dahlhaus, David; Warwas, Dawid Peter; Meißner, Jessic; Taptimthong, Piriya; Kietzmann, Manfred; Behrens, Pete; Reifenrath, Janin; Angrisani, Nina (Berlin : Springer Nature, 2018)

Background: In orthopedic surgery, implant-associated infections are still a major problem. For the improvement of the selective therapy in the infection area, magnetic nanoparticles as drug carriers are promising when ...
In vitro evaluation of PCL and P(3HB) as coating materials for selective laser melted porous titanium implants

Grau, Michael; Matena, Julia; Teske, Michael; Petersen, Svea; Aliuos, Pooyan; Roland, Laura; Grabow, Niels; Escobar, Hugo Murua; Gellrich, Nils-Claudius; Haferkamp, Heinz; Nolte, Ingo (Basel : MDPI AG, 2017)

Titanium is widely used as a bone implant material due to its biocompatibility and high resilience. Since its Young's modulus differs from bone tissue, the resulting "stress shielding" could lead to scaffold loosening. ...
In vivo assessment of the host reactions to the biodegradation of the two novel magnesium alloys ZEK100 and AX30 in an animal model

Huehnerschulte, Tim Andreas; Reifenrath, Janin; Rechenberg, Brigitte von; Dziuba, Dina; Seitz, Jan-Marten; Bormann, Dirk; Windhagen, Henning; Meyer-Lindenberg, Andrea (London : BioMed Central Ltd, 2012)

Background: Most studies on biodegradable magnesium implants published recently use magnesium-calcium-alloys or magnesium-aluminum-rare earth-alloys. However, since rare earths are a mixture of elements and their toxicity ...
In vivo degradation behavior of the magnesium alloy land442 in rabbit tibiae

Ullmann, Berit; Reifenrath, Janin; Dziuba, Dina; Seitz, Jan-Marten; Bormann, Dirk; Meyer-Lindenberg, Andrea (Basel : MDPI AG, 2011)

In former studies the magnesium alloy LAE442 showed promising in vivo degradation behavior and biocompatibility. However, reproducibility might be enhanced by replacement of the rare earth composition metal "E" by only a ...
In vivo testing of a bioabsorbable magnesium alloy serving as total ossicular replacement prostheses

Lensing, Rebecca; Behrens, Peter; Müller, Peter Paul; Lenarz, Thomas; Stieve, Martin (London : SAGE Publications Ltd., 2014)

Magnesium alloys have been investigated in different fields of medicine and represent a promising biomaterial for implants due to characteristics like bioabsorbability and osteoinduction. The objective of this study was ...
The influence of storage and heat treatment on a magnesium-based implant material: An in vitro and in vivo study

Bracht, Katja; Angrisani, Nina; Seitz, Jan-Marten; Eifler, Rainer; Weizbauer, Andreas; Reifenrath, Janin (London : BioMed Central Ltd., 2015)

Background: Magnesium alloys are recommended as a potential material for osteosynthesis. It is known that storage-induced property modifications can occur in materials like aluminum. Thus the aim of this study was to analyze ...
Laser powder bed fusion of WE43 in hydrogen-argon-gas atmosphere

Abel, Arvid; Wessarges, Yvonne; Julmi, Stefan; Hoff, Christian; Hermsdorf, Jörg; Klose, Christian; Maier, Hans Jürgen; Kaierle, Stefan; Overmeyer, Ludger (Amsterdam : Elsevier B.V., 2020)

Growing demand for individual and especially complex parts with emphasis on biomedical or lightweight applications enhances the importance of laser powder bed fusion. Magnesium alloys offer both biocompatibility and low ...

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