Auflistung nach Autor/in "81cd0401-63e9-4d55-beb8-2428070e0121"

Auflistung nach Autor/in "81cd0401-63e9-4d55-beb8-2428070e0121"

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  • Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages 
    Shahraz, Anahita; Kopatz, Jens; Mathy, Rene; Kappler, Joachim; Winter, Dominic; Kapoor, Shoba; Schuetza, Vlad; Scheper, Thomas; Gieselmann, Volkmar; Neumann, Harald (London : Springer Nature, 2015)
    Oligosialic and polysialic acid (oligoSia and polySia) of the glycocalyx of neural and immune cells are linear chains, in which the sialic acid monomers are alpha 2.8-glycosidically linked. Sialic acid-binding immunoglobulin-like ...
  • Polysialic acid production using Escherichia coli K1 in a disposable bag reactor 
    de Vries, Ingo; Busse, Christoph; Kopatz, Jens; Neumann, Harald; Beutel, Sascha; Scheper, Thomas (Weinheim : Wiley-VCH Verlag, 2017)
    Polysialic acid (polySia), consisting of α-(2,8)-linked N-acetylneuraminic acid monomers plays a crucial role in many biological processes. This study presents a novel process for the production of endogenous polySia using ...
  • Single-use membrane adsorbers for endotoxin removal and purification of endogenous polysialic acid from Escherichia coli K1 
    de Vries, Ingo; Schreiber, Sarah; Boßmann, Daniel; Hellmann, Zawadi; Kopatz, Jens; Neumann, Harald; Beutel, Sascha (Amsterdam : Elsevier B.V., 2018)
    Polysialic acid (polySia) is a promising molecule for various medical applications (e.g., treatment of inflammatory neurodegenerative diseases). In this study a complete production process for human-identical α-(2,8)-linked ...